This paper describes an investigation of microfluidic actuation of doublet patterns in samples of water on blank substrates, using singular and arrayed microfabricated thermal probes. A doublet is a twodimensional flowpattern consistingof adjacent, opposing vorticeswith linear streamlines between them. In thiswork, each probe consists of a polyimide thin film cantileverwith ametal heater near t...

We consider the dynamics of self-propelled particles subject to external torques. Two models for the reorientation of self-propulsion are considered: run-and-tumble particles and active Brownian particles. Using the standard tools of nonequilibrium statistical mechanics we show that the run and tumble particles have a more robust response to torques. This macroscopic signature of the underlying...

Escherichia coli cells treated with arsenate cannot tumble. The relationship between cellular adenosine 5'-triphosphate (ATP) level and the ability to tumble has been studied. (i) Cells incubated with arsenate completely lost their tumbling ability, and the cellular ATP level was decreased to less than 0.3 nmol/mg of protein. (ii) Incubation with 10 mM arsenate-1 mM phosphate reduced the cellul...

Understanding how bacteria move close to a surface under various stimuli is crucial for a broad range of microbial processes including biofilm formation, bacterial transport and migration. While prior studies focus on interactions between single stimulus and bacterial suspension, we emphasize on compounding effects of flow shear and solid surfaces on bacterial motility, especially reorientation...

The design of an active leg orthosis for tumble protection is proposed in this paper. The orthosis would be applied to assist elders or invalids in rebalancing while they fall unexpectedly. We observe the regain balance motion of healthy and youthful people, and find the difference to elders or invalids. First, the physical model of leg would be established, and we consider the leg motions are ...

Run-and-tumble motility is widely used by swimming microorganisms including numerous prokaryotic and eukaryotic organisms. Here, we experimentally investigate the run-and-tumble dynamics of the bacterium E. coli in polymeric solutions. We find that even small amounts of polymer in solution can drastically change E. coli dynamics: cells tumble less and their velocity increases, leading to an enh...

Animal cells can sense chemical gradients without moving, and are faced with the challenge of migrating towards a target despite noisy information on the target position. Here we discuss optimal search strategies for a chaser that moves by switching between two phases of motion (run and tumble), reorienting itself towards the target during tumble phases, and performing a persistent random walk ...

BACKGROUND Positive emotions have been shown to induce resilience to depression and anxiety in humans, as well as increase cognitive abilities (learning, memory and problem solving) and improve overall health. In rats, frequency modulated 50-kHz ultrasonic vocalizations (Hedonic 50-kHz USVs) reflect a positive affective state and are best elicited by rough-and-tumble play. METHODS The effect ...