The aim of this study was to verify the trypanocidal effectiveness of aqueous, methanolic, and ethanolic extracts of Achyrocline satureioides against Trypanosoma evansi in vitro. A. satureioides extracts, known as macela, were used on trypomastigotes at different concentrations (1, 5, 10, 50, 100, 500, and 1,000 µg/ml) and exposure times (0, 1, 3, 6, and 9 hr). A dose-dependent effect was obser...

Trypanosoma evansi causes wasting disease in many livestock. T. evansi infection gives rise to inflammatory immune responses, which contribute to the development of inflammation-associated tissue injury. We previously reported that regulatory dendritic cells (DCs), which act as potential regulators of inflammation, were activated in infected mice and transfer of regulatory DCs to infected mice ...

Trypanosomosis was recorded in a buffalo during the month of September 2014 in Proddatur of Andhra Pradesh, India. Disease was confirmed by the presence of Trypanosoma evansi organisms in peripheral blood smears. Buffalo was treated with intra muscular administration of diminazene aceturate at the rate of 3.5 mg per kg body weight along with supportive therapy. After two days of therapy, re-exa...

There is increasing interest in many parts of the world in trypanosomoses other than those transmitted by tsetse flies, as shown by numerous research projects and field studies. The refinement of techniques for studying the behaviour of trypanosomes (techniques of molecular biology) in axenic culture or in the parasitised host has led to progress in diagnosis and immunology, and a rational appr...

Background: Based on the recently sequenced gene coding for the Trypanosoma evansi (T. evansi) RoTat 1.2 Variable Surface Glycoprotein (VSG), a primer pair was designed targeting the DNA region lacking homology to other known VSG genes. A total of 39 different trypanosome stocks were tested using the RoTat 1.2 based Polymerase Chain Reaction (PCR). Results: This PCR yielded a 205 bp product in ...

The impact of three treatment strategies for Trypanosoma evansi control on horse mortality in the Brazilian Pantanal based on four size categories of cattle ranches is explored. The region's 49,000 horses are indispensable to traditional extensive cattle ranching and T. evansi kills horses. About 13% of these horses would be lost, annually, due to T. evansi if no control were undertaken. One pr...

Trypanosomiasis is an important protozoan disease of domestic animals and man. One the pathogenic trypanosomes in Trypanosoma evansi; causative agent Surra that highly fatal to a number domesticated mammals such as camels. Mentha longifolia plant has been used traditional medicine treat some parasitic microbial diseases different countries. This study was conducted evaluate antitrypanosomal act...

We evaluated the clinical, parasitological and immunological effects of a Venezuelan strain of Trypanosoma evansi (T. evansi) throughout in experimentally inoculated rabbits over the course of infection and compared them with the same aspect in healthy animals. Body temperature was recorded in degrees Celsius, animal weight in kilograms, serum proteins in g/dl using a refractometer, haematocrit...

Surra is a disease caused by the hemoflagellate pathogen Trypanosoma evansi which affects wide variety of mammals. The only cases reported presence T. in Paraguay were identified samples from horses and capybaras they detected light microscopy 19th century. aim this study to report three autochthonous canine trypanosomiasis evansi, for first time country, using molecular techniques their applic...

Trypanosoma brucei is a kinetoplastid flagellate, the agent of human sleeping sickness and ruminant nagana in Africa. Kinetoplastid flagellates contain their eponym kinetoplast DNA (kDNA), consisting of two types of interlocked circular DNA molecules: scores of maxicircles and thousands of minicircles. Maxicircles have typical mitochondrial genes, most of which are translatable only after RNA e...