We report a case of Klinefelter's syndrome owing to maternal meiotic error associated with triphalangeal thumb and delta phalanx bilaterally. There are no previous reports of similar cases and triphalangism with delta phalanx abnormalities of both thumbs might therefore be considered a further, but rare, manifestation of this aneuploidy.

Townes-Brocks syndrome (TBS) is an autosomal dominant disorder with multiple malformations and variable expression. Major findings include external ear anomalies, hearing loss, preaxial polydactyly and triphalangeal thumbs, imperforate anus, and renal malformations. Most patients with Townes-Brocks syndrome have normal intelligence, although mental retardation has been noted in a few. (J Med Ge...

triphalangeal thumb is characterized by the interposition of an extra-phalanx between two normal ones. in this article the authors present the case of a 24-year-old man with bilateral triphalangeal thumb of opposable type, without any other associated anomaly or genetic syndrome. the patient had triangular delta extra-phalanxes that caused ulnar deviation of both thumbs. surgical procedure for ...

This report describes a 2-month-old female with the Aase syndrome, bringing to 8 the total number of cases of this disorder. Features include triphalangeal thumbs and congenital hypoplastic anaemia. The occurrence of this disorder in sibs born to unaffected parents and in both sexes makes autosomal recessive inheritance the most likely aetiology.

In this study, removal of a transitional object (pillow) was applied as the sole intervention for one of two siblings who sucked their thumbs. The intervention was applied only to the older sibling, whereas data were collected on the thumb sucking of both participants. Results indicated that removal of the transitional object for the older sibling reduced thumb sucking in both siblings and incr...