background: diabetic retinopathy is the major cause of blindness among working-age population across the world. despite the urgent need for research strategic planning in this field, no systematic research has been previously performed analyzing the published research on diabetic retinopathy. the study aimed to analyze the scientific productions on dr for drawing a general roadmap for future re...

in this paper an efficient dual time implicit approach is used to solve viscous laminar flow around two bodies with general motion. therefore, the grid includes a background grid and two sets of grids around the moving bodies. rotational and translational motions of two bodies are managed separately in this grid arrangement. in this work the overset concept for hybrid grid is used and flow vari...

the rapid melting of a semi- infinite body due to the absorption of a cw laser beam radiation has been studied. the enthalpy technique for the solution of phase change problems has been used in an explicit finite difference form to calculate the transient temperature distribution in the semi-infinite body and the growth rate of the melt pool. the technique has been modified so that it is not ne...

Context:MicroRNAs (miRNAs) are a class of short, endogenously-initiated, non-coding RNAs that post-transcriptionally control gene expression via translational repression or mRNA turnover. MiRNAs have attracted much attention in recent years as they play critical roles in gene expression and are promising tools with many biotech and therapeutic applications. The molecular mechanisms und...

1- Department of Medical History, School Persian Medicine, Tehran University Sciences, Tehran, Iran 2- Translational Ophthalmology Research Center, Farabi Eye Hospital, , [email protected]

the thioredoxin system, comprising thioredoxin (trx), thioredoxin reductase (trxr) and nadph, is one of the major cellular antioxidant systems, implicated in a large and growing number of biological functions. trx acts as an oxidoreductase via a highly conserved dithiol/disulfide motif located in the active site ( trp-cys-gly-pro- cys-lys-). different factors are involved in the regulation of t...

This paper presents nonlinear elastic dynamic analysis of 3-D semi-rigid steel frames including geometric and connection nonlinearities. The geometric nonlinearity is considered by using stability functions and updating geometric stiffness matrix. The nonlinear behavior of the steel beam-to-column connection is considered by using a zero-length independent connection element comprising of six t...