abstract   synchronous upper urinary tract tumor and superficial bladder tumor are uncommon. this is a report of a 62- year- old man presented with episode of painless gross hematuria and flank pain. we worked him up and found a left renal mass and bladder lesion. he underwent nephrectomy and tur-bt, and the pathology report of both showed a high grade urothelial transitional cell carcinoma. th...

background: the present study was undertaken to investigate the correlation of epidermal growth factor receptor (egfr) expression with grade of transitional cell carcinoma (tcc). methods: tumor samples of 75 patients from mostafa khomaini hospital with transitional cell carcinoma of the bladder were analyzed by immunohistochemistry for expression of egfr. in this context, we assigned the bladde...

objective: transitional cell carcinoma (tcc) of the urinary bladder is the second common cancer of the genitourinary tract. several parameters such as clinical and pathological parameters, molecular factors, and etc play a role in determination of prognosis and type of treatment. in this research study, the relationship between grade and mdm2 oncoprotein overexpression in tcc of bladder was eva...

PURPOSE To compare the expression of survivin and its association with clinicopathological criteria in major types of urinary bladder carcinoma, specifically, transitional cell carcinoma with and without squamous differentiation and squamous cell carcinoma. MATERIALS AND METHODS Immunohistochemical staining for survivin and Ki67 was performed on paraffin-embedded sections of 104 carcinomas: 5...

All transitional cell carcinomas of the bladder diagnosed in male patients within a five year period were studied for human chorionic gonadotropin (hCG) production. Biotin-avidin immunoperoxidase analysis for hCG was performed on all paraffin blocks containing carcinoma-in-situ, grade I, grade II, and grade III transitional cell carcinoma. Of a total of 29 patients, one case of carcinoma-in-sit...

OBJECTIVE We report a rare case of malignant priapism secondary to transitional cell carcinoma. METHODS The patient with bladder cancer (pT4G3) presented with painful penile erection. Corpora cavernosa biopsy was done. RESULTS The pathologic diagnosis was penile metastasis of transitional cell carcinoma. CONCLUSIONS Priapism secondary to penile metastasis of transitional cell carcinoma is...

The aim of this study was to evaluate the diagnostic value of AgNOR (Argyrophilic Nucleolar Organizer Proteins Region) staining in differentiation between malignant and non-malignant lesion, and histological grading of bladder transitional cell carcinoma. We have also showed the rate of AgNOR distribution score in the nuclear of malignant and non-neoplastic cells of bladder epithelium as an imp...

AIMS AND BACKGROUND Upper urinary tract transitional cell carcinoma, a relatively rare tumor, is up to 100 times more frequent in regions with Balkan endemic nephropathy. Characteristics of transitional cell carcinoma in the endemic South Morava Region in Serbia in the previous 50 years were evaluated. PATIENTS We analyzed 477 cases with pathologically confirmed transitional cell carcinoma wh...