نتایج جستجو برای: transforming growth factor beta
تعداد نتایج: 1626309 فیلتر نتایج به سال:
acute myeloblastic leukemia is the most frequent cancer in adults and the patients have a wide range of sub-classes. hla dr negative cases represent one of the major immune-phenotypic classes. hla-dr is routinely used to distinguish acute promyelocytic leukemia (apl) from other aml subclasses based on the immunophenotype. the tgf-b signaling pathway, as a critical regulator, guides different v...
background: osteoarthritis is one of the most common diseases in middle‑aged populations in the world and could become the fourth principal cause of disability by the year 2020. one of the critical properties for cartilage tissue engineering (te) is the ability of scaffolds to closely mimic the extracellular matrix and bond to the host tissue. therefore, te has been presented as a technique to ...
Transforming growth factor-beta, a potent modulator of cell function, induces fibroblasts cultured on plastic to increase collagen synthesis. In 5- and 7-day porcine skin wounds, which have minimal to moderate collagen matrix, respectively, transforming growth factor-beta and type I procollagen were coordinately expressed throughout the granulation tissue. However, in 10-day collagen-rich granu...
Overproduction of transforming growth factor-beta clearly underlies tissue fibrosis in numerous experimental and human diseases. Transforming growth factor-beta's powerful fibrogenic action results from simultaneous stimulation of matrix protein synthesis, inhibition of matrix degradation, and enhanced integrin expression that facilitates matrix assembly. In animals, overexpression of transform...
Introduction: Systemic lupus erythematosus (SLE) is a chronic systemic inflammatory autoimmune disease characterized by a breakdown of self-tolerance. Transforming growth factor-β1 is a cytokine produced by both immune and non immune cells, and it has a wide operating range. human TGF-β1 gene is located on chromosome 19q13 . The aim of this study was investigating the TGF-β1 Gene...
Purpose: Effects of TGF-b and b-FGF on the Potential of Peripheral Blood-Borne Stem Cells and Bone Marrow-Derived Stem Cells In Wound Healing in a Murine Model.Materials and Methods: Peripheral blood mesenchymal stem cells (PBMSCs) and bone marrow stem cells (BMSCs) cultured in media with transforming growth factor-beta (TGF-b) and basic fibroblast growth factor (b-FGF). Stem cells labeled with...
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