the application of low-frequency ultrasound for transdermal delivery of insulin is of particular public interest due to the increasing problem of diabetes. the purpose of this research was to develop an air ultrasonic ceramic transducer for transdermal insulin delivery and evaluate the possibility of applying a new portable and low-cost device for transdermal insulin delivery. twenty-four rats ...

Topically applied pharmaceuticals in the form of patches that distribute medications for systemic effects at predefined and controlled rates are known as "transdermal drug delivery systems." The main function TDDS is penetration through skin. It works extremely simple, with medicine being put within patch placed on As a result, consistent concentration medication remains bloodstream an extended...

Transdermal drug delivery system offers best way of through skin than compared to oral route administration by overcoming side-effects.Drug is done adhesion transdermal patches surface.Novel application techniques have been employed for better therapeutic response various in treatment several disease using dermal administration.This non-invasive method reducing frequency achieve complete action...

the aim of the present study was to develop and investigate the feasibility of delivering nebivolol as a transdermal patch by iontophoresis. the passive and electrically assisted transdermal delivery of nebivolol hydrochloride by iontophoresis will improve the therapeutic efficacy and overcome the difficulties raised in oral drug delivery. because of its extensive hepatic metabolism and low dos...

As skin is a readily accessible organ of the body, it acts as the portal of entry for extraneous substances for their effective transdermal delivery. Possessing various advantages, it has the limitation of low permeability of drugs across it, limiting the efficacy of drugs. Therefore, various carrier systems have been developed to enhance the permeation deep into the systemic circulation. The p...

Transdermal drug delivery (TDD) is a non-invasive route of drug administration, although its applications are limited by low skin permeability. It is an attractive alternative technique over the conventional techniques for administration of systemic approaches. For both local and systemic effects skin is the major site of application. However, to penetrate the drug through skin, stratum corneum...