BACKGROUND Adenoviral-targeted gene delivery to respiratory epithelium can augment production of specific proteins. Therefore, it may be valuable in treating the acute respiratory distress syndrome. The authors tested the hypothesis that adenoviral vector uptake after cecal ligation and double puncture in rats, an animal model of the acute respiratory distress syndrome, is higher than that obse...

Adenosine induces dyspnea, cough, and airways obstruction in asthma, a phenomenon that also occurs in various sensitized animal models in which a neuronal involvement has been implicated. Although adenosine has been suggested to activate cholinergic nerves, the precise mechanism has not been established. In the present study, the adenosine A(1) receptor agonist N(6)-cyclopentyladenosine (CPA) i...

conclusions the ligation method with attention to the modifications described further in the article is a simple, safe and cost effective option for the management of urethral prolapse.rnmaintaining the inflated balloon of the foley catheter with timed catheter removal especially adds predictability to this technique. results the mean age of the patients was 6 years old (ranging from 3 to 8 yea...

  Introduction: Tracheal stenosis is normally caused by trauma, infection, benign and malignant tumors, prolonged intubation or tracheostomy. The best treatment for tracheal stenosis is resection and anastomosis of trachea. Yet the major surgical complication of tracheal surgery is postoperative stenosis. The goal of this paper is to study the result of tracheal stenting as a replacement therap...

Background: Tubal ligation is one of the most common contraceptive methods in the world. Some researchers believe that tubal ligation has complications. It is assumed oxidative stress can produce these complications. The aim of this study was to evaluate oxidative stress and ovarian function after tubal ligation. Materials and Methods: In this study, female rats (weighting 200-250 g) were divid...

objective: despite development of new contraceptive methods, sterilization remained the most widely used method. our objective was to determine the factors contributing to decision making for tubal ligation in females. materials and methods: a cross sectional study was conducted in jinnah post graduate medical centre (jpmc) between march - november 2008. about 505 females using contraceptive me...

Abstract Beyond cell-cell contact, communication at a distance requires the secretion of cytokines that bind to specific receptors on responsive cells. Interleukin (IL)-9 is cytokine with pleiotropic effects not only immune cells contribute progression tumor and autoimmunity, but also structural including airway intestinal epithelial involved in development inflammatory allergic diseases. Typic...

BACKGROUND Symptomatic obstruction of long-segment tracheal or bronchial portions either related to congenital instability or secondary to vascular compression are rare malformations, which remain difficult to manage. A method of external tracheal or bronchial stabilization is described. METHODS From July 1992 to April 1995, 7 children (age range, 4 months to 4 years; mean age, 19 months) and...

background: reversal of tubal ligation is requested by some women for various reasons. the present study aims to determine the rate of pregnancy after tubal ligation reversal. case: in these case series, we reported fifteen women who requested tuboplasty after tubal ligation. in these cases reversal of tubal ligation was done in 15 women. pregnancy occurred in 4 women (26.6%). two term pregnanc...

Tissue factor (TF) is a critical mediator of direct acute lung injury (ALI) with global TF deficiency resulting in increased airspace inflammation, alveolar-capillary permeability, and alveolar hemorrhage after intra-tracheal lipopolysaccharide (LPS). In the lung, TF is expressed diffusely on the lung epithelium and intensely on cells of the myeloid lineage. We recently reported that TF on the ...