13353 BI-H-1013-001 HONORS BIOL OF THE CELL U 3 GRIPPO A MTG1-TR 0930AM-1100AM LSE 207 10990 EN-H-1013-001 HONORS FR ENGLISH II U 3 MCGHEE R MTG1-MWF 0900AM-0950AM W 315 10991 EN-H-1013-002 HONORS FR ENGLISH II U 3 SCHICHLER R MTG1-TR 1100AM-1215PM LIB 103B 10992 EN-H-1013-003 HONORS FR ENGLISH II U 3 CHAPPEL D MTG1-MWF 1200PM-1250PM LIB 103B 10993 EN-H-2013-001 HNRS INTRO LIT II U 3 COLLINS J ...

BACKGROUND The cell surface receptor (uPAR) for urokinase plasminogen activator (uPA) is a strong prognostic marker in several types of cancer. uPA cleaves the three-domain protein uPAR(I-III) into two fragments: uPAR(I), which contains domain I; and uPAR(II-III), which contains domains II and III. Established immunoassays measure a combination of uPAR forms. Our aim was to design immunoassays ...

The intent of this study was to determine whether endurance exercise training regulates increases in metabolic enzymes, which parallel modulations of myogenin and MyoD in skeletal muscle of rats. Adult Sprague-Dawley rats were endurance trained (TR) 5 days weekly for 8 wk on a motorized treadmill. They were killed 48 h after their last bout of exercise. Sedentary control (Con) rats were killed ...

The alkali-metal gold trielides K(3)Au(5)Tr (Tr = In (I), Tl (II)) and Rb(2)Au(3)Tl (III) have been obtained directly from the elements, and their orthorhombic structures determined by single-crystal X-ray diffraction means (I/II: Imma, a = 5.562(1), 5.595(1); b = 19.645(4),19.706(4); c = 8.502(2), 8.430(2) A; Z = 4, respectively; III: Pmma, a = 5.660(1), b = 6.741(1), c = 9.045(2) A, Z = 4). T...

Targeting of MHC class II molecules to the endocytic compartment where they encounter processed antigen is determined by the invariant chain (Ii). By analysis of Ii-transferrin receptor (TR) chimera trafficking, we have identified sorting signals in the Ii cytoplasmic tail and transmembrane region that mediate this process. Two non-tyrosine-based sorting signals in the Ii cytoplasmic tail were ...

A truncated form of the c-kit tyrosine kinase receptor, corresponding to the phosphotransferase portion of the cytoplasmic catalytic domain and the carboxyterminus (tr-kit), is accumulated during late mouse spermiogenesis. Here we report that tr-kit is specifically localized in the residual sperm cytoplasm, with maximal accumulation in the midpiece of the flagellum, suggesting that it can enter...

Abstract Background Mitral regurgitation (MR) and tricuspid (TR) often occur simultaneously symptoms of biventricular heart failure can overlap. There is currently no consensus on the management combined MR TR. Purpose To evaluate impact TR echocardiographic functional outcome after M-TEER. Methods 740 patients underwent M-TEER for moderate-to-severe at our center from 2010 to 2021. Patients we...

The effect of protein kinase inhibitors on transferrin receptor (TR) internalization was examined in HeLa, A431, 3T3-L1 cells, and primary chicken embryo fibroblasts. We show that TR endocytosis is not affected by tyrosine kinase or protein kinase C inhibitors, but is inhibited by one serine/threonine kinase inhibitor, H-89. Inhibition occurred within 15 min, was completely reversible after H-8...