This study aimed to observe the protective effects of sufentanil pretreatment on rat cerebral injury during cardiopulmonary bypass (CPB) and to explore the underlying mechanism. Twenty-four male adult Sprague Dawley (SD) rats were divided into 4 groups. Then, the rat CPB model was established. A 14G trocar was inserted into the atrium dextrum. For rats in S1 and S5 groups, sufentanil (1 µgKg(-1...

Introduction: A relationship between epileptic seizures and brain tissue oxidative damage has been suggested. Ocimum basilicum (O. basilicum) has been shown to have beneficial effects including hypnotic and protective against tissue oxidative damage. The present study was designed to evaluate the effects of O. basilicum hydro-alcoholic extract on oxidative damage of brain tissue following s...

the comparison of total and ionised serum calcium level in preeclamptic pregnant women and the women with normal pregnancy   z. salari md1*, n. eftekhari md2     1- assistan professor, dept of gynecology, university of medical sciences, kerman, iran 2- associated professor, dept of gynecology, university of medical sciences, kerman, iran     background: preeclampsia remains one of the important...

Seizure activity has been proposed to result in the generation of reactive oxygen species (ROS), which then contribute to seizure-induced neuronal damage and eventually cell death. Although the mechanisms of seizure-induced ROS generation are unclear, mitochondria and cellular calcium overload have been proposed to have a crucial role. We aim to determine the sources of seizure-induced ROS and ...

convulsion is one of the most common problems in children and hypocalcemia is one the most frequent etiological items in children’s convulsion. corrected qt (qtc) in ekg is prolonged in hypocalcemia, so it can be a useful tool for evaluation of serum ionized calcium. in three groups (first seizure, multiple seizures, without seizure or control ) every 25 cases, qtc, serum ionized ca, total ca, ...

seizure activity has been proposed to result in the generation of reactive oxygen species (ros), which then contribute to seizure-induced neuronal damage and eventually cell death. although the mechanisms of seizure-induced ros generation are unclear, mitochondria and cellular calcium overload have been proposed to have a crucial role. we aim to determine the sources of seizure-induced ros and ...

brain injury has a multiple pathophysiology for which there is no definite treatment. in this regard, tissue engineering is one of the probable strategies for repair of damaged tissue. but creating a proper model for testing the engineered products faced some difficulties, specially, when we want to evaluate the effects of a product on the volume of injury. the current brain injury methods coul...

the type of training system and application of calcium spray have considerable effects on storability of fruits. in this study, the effects of calcium chloride spray (0, 0.75, 1.5 and 3 g.l-1) in three times during 2, 4 and 6 weeks before harvest time on apple (malus domestica) fruits cvs. ‘gala’ and ‘delbarestival’, which trained in three different training systems (v shape, hightech and cordo...