INTRODUCTION Polymorphous low-grade adenocarcinoma is a distinct neoplasm of the salivary gland composed of luminal and non-luminal tumor cells admixed in varying proportions. Its resemblance to lobular carcinoma of the breast had led to its earlier nomenclature of 'terminal duct carcinoma'. Most patients present with an asymptomatic mass in the hard palate. In rare cases, the mass can also occ...

Granular cell tumor (GCT) is an uncommon neoplasm of controversial origin that can appear in any corporal localization, including the orofacial region. Although aggressive and malignant variants of this neoplasm have been described, most of GCTs are benign. In spite of the amount of research, the etiology of this neoplasm remains unclear and its histogenesis and its possible muscular, connectiv...

INTRODUCTION This article presents the case of a 26-year-old woman with tongue cancer. The median age at the diagnosis of the tongue's cancer is 61 years. Only approximately 2% of patients are diagnosed before the age of 35. CASE PRESENTATION Our patient survived acute myeloid leukemia (AML) before her second year. She had been having recurrent, poorly healing aphtae on the right side of the ...

To cite: Crawford JR, Newbury RO, Friedman JR. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-010267 DESCRIPTION A 15-year-old girl with a history of congenital nystagmus presented with newly recognised hyperkinetic tongue movements on protrusion without dysphagia, dysphonia or palatal myoclonus (see online supplementary video). Contrast-enhanced MRI reveal...

P rimary malignant melanoma of the oral cavity is a rare neoplasm. The incidence of oral cavity melanoma is about 0.2%–8.0% of all malignant melanoma cases. Primary lesions arising from oral mucosa occur most frequently on the maxillary gingiva and palate, with the lips being the third most frequent. Melanoma of the tongue is specifically uncommon and represents less than 2% of all oro-nasal me...

Tuberculosis (TB) of the tongue is not a common finding diagnosis, even if consider endemic areas. Tuberculosis of the tongue sometimes can mimic lingual neoplasm. Oral tuberculosis is rarely primary as mechanism, and frequently secondary to pulmonary tuberculosis. There are many suspect lesions that can be classified as tuberculosis, such as tumor mass, ulcerative lesion or fissure. It is very...

Note: An invasive epithelial neoplasm with varying degrees of squamous differentiation that arises from the following anatomic sites: the oral cavity, particularly oral soft tissues including the gingival and alveolar mucosa, floor of the mouth, tongue, soft and hard palates, tonsils and oropharynx. Oral squamous cell carcinomas (SCC) have a propensity to early and extensive lymph node metastases.

Granular cell tumor is a rare benign neoplasm most commonly appears in the head and neck region, especially in the tongue, cheek mucosa, and palate. Occurrence in limbs is even rarer. These tumors account for approximately 0.5% of all soft tissue tumors. Granular cell tumor can also affect other organs including skin, breast, and lungs. Local recurrence and metastasis is potentially higher in m...