Measuring a time interval in the nanoseconds range has opened way to 3-D imaging, where additional information as distance of objects light detection and ranging (LiDAR) or lifetime decay fluorescence-lifetime imaging (FLIM) is added spatial coordinates. One key elements these systems measurement circuit, which encodes into digital words. Nowadays, most demanding applications, especially biolog...

in many signal processing applications, an appropriate measure to comparetwo signals plays a fundamental role in both implementing the algorithm andevaluating its performance. several techniques have been introduced in literature assimilarity measures. however, the existing measures are often either impractical forsome applications or they have unsatisfactory results in some other applications....

Polydatin (PD), a resveratrol glucoside extracted from the perennial herbage Polygonum cuspidatum, has been suggested to have wide cardioprotective effects. This study aimed to explore the direct antihypertrophic role of PD in cultured neonatal rat ventricular myocytes (NRVMs) and its therapeutic effects against pressure overload (PO)-induced hypertrophic remodeling and heart failure. Furthermo...

Ding W, Dong M, Deng J, Yan D, Liu Y, Xu T, Liu J. Polydatin attenuates cardiac hypertrophy through modulation of cardiac Ca handling and calcineurin-NFAT signaling pathway. Am J Physiol Heart Circ Physiol 307: H792–H802, 2014. First published July 11, 2014; doi:10.1152/ajpheart.00017.2014.—Polydatin (PD), a resveratrol glucoside extracted from the perennial herbage Polygonum cuspidatum, has be...

the rapid scaling in modern cmos technology has motivated the researchers to design new analog-to-digital converter (adc) architectures that can properly work in lower supply voltage. an exchanging the data quantization procedure from the amplitude to the time domain, can be a promising alternative well adapt with the technology scaling. this paper is going to review the recent development in t...

The rapid scaling in modern CMOS technology has motivated the researchers to design new analog-to-digital converter (ADC) architectures that can properly work in lower supply voltage. An exchanging the data quantization procedure from the amplitude to the time domain, can be a promising alternative well adapt with the technology scaling. This paper is going to review the recent development in t...

The challenging task to synthesize automatically a time-to-amplitude converter, which unites by its functionality several digital circuits, has been successfully solved with the help of a novel methodology. The proposed approach is based on a paradigm according to which the substructures are regarded as additional mutation types and when ranged with other mutations form a new adaptive individua...

Time-Correlated Single-Photon Counting (TCSPC) is an excellent technique used in a great variety of scientific experiments to acquire exceptionally fast and faint light signals. Above all, Fluorescence Lifetime Imaging (FLIM), it widely recognized as the gold standard record sub-nanosecond transient phenomena with picosecond precision. Unfortunately, TCSPC has intrinsic limitation: avoid so-cal...