background: in survival studies when the event times are dependent, performing of the analysis by using of methods based on independent assumption, leads to biased. in this paper, using copula function and considering the dependence structure between the event times, a parametric joint distribution has made fitting to the events, and the effective factors on each of these events would be determ...

Any theory that purports to explain how phenomenal experience arises in the system in question (such as the brain) must do so in terms that are meaningful within the system itself. Simply put, because my experience of the world cannot be up to an outside observer, it cannot be explained by positing entities, such as whole-brain state variables, if those can only be known from the outside. This ...

Abstract Event-triggered control (ETC) and time-triggered (TTC), the classical concepts to determine transmission instants for networked systems, each come with drawbacks: It is difficult tune ETC such that a certain bandwidth respected, whereas TTC cannot adapt sampling interval current state of system. In this article, we provide an overview over rollout ETC, method aimed at reconciling advan...

The natural end point of clinical trials is often the time to an event. The event under consideration may be undesirable, such as disease progression or death, in which case the purpose of a trial would be to maximize the time to this event. Alternatively, the event being studied may be desirable, such as time to transplant engraftment, in which case the trial would seek to minimize the time to...