the objectives of the present study were to investigate the prevalence of histologic thyroids lesions and the respective thyroid hormones changes of ewes in an endemic goiter region and to find out any impact of this condition on the fetal thyroid structures and serum thyroid hormones. in the present study a total number of 100 pregnant ewes and their fetuses slaughtered at slaughterhouse were ...

Selective iodide uptake and prolonged iodine retention in the thyroid is the basis for targeted radioiodine therapy for thyroid cancer patients; however, salivary gland dysfunction is the most frequent nonthyroidal complications. In this study, we have used noninvasive single photon emission computed tomography functional imaging to quantify the temporal dynamics of thyroidal and salivary radio...

Sagreiya, K., and Emery, J. L. (1970). Archives of Disease in Childhood, 45, 746. Perinatal thyroid discharge: a histological study of 1225 infant thyroids. A random sample of 500 infant thyroids in which post-mortem changes were, as far as possible, eliminated was studied histologically. In the great majority ofneonatal thyroids there are distinct changes which suggest the occurrence of an acu...

Methods and Materials The weight of the thyroid was estimated in 125 Jamaican negro infants aged 3 months to 3 years. The nutritional state of most of the infants was easy to assess, but in a few instances it had to be decided by paying attention to the social and dietary history and by comparing heights and weights with percentile values quoted by Stuart and Stevenson (1950). Of the 125 infant...

BACKGROUND The molecular mechanisms driving the papillary thyroid carcinoma (PTC) are still poorly understood. The most frequent genetic alteration in PTC is the BRAFV600E mutation--its impact may extend even beyond PTC genomic profile and influence the tumor characteristics and even clinical behavior. METHODS In order to identify BRAF-dependent signature of early carcinogenesis in PTC, a tra...

Calmodulin levels in normal human thyroids and Graves' disease thyroids were measured by specific radioimmunoassay in the presence of ethyleneglycol-bis-(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA). The calmodulin levels in tissues from patients with Graves' disease treated with thionamide drugs were significantly higher than those in normal tissues from euthyroid patients with sol...

Studies have suggested that the nuclear receptor corepressor 1 (NCOR1) could play an important role in human cancers. However, the detailed molecular mechanisms by which it functions in vivo to affect cancer progression are not clear. The present study elucidated the in vivo actions of NCOR1 in carcinogenesis using a mouse model (Thrb(PV/PV) mice) that spontaneously develops thyroid cancer. Thr...

Mediastinal ectopic thyroid is quite rare, occurring in less than 1% of all ectopic thyroids. Frequent location of mediastinal ectopic thyroid in reported cases is anterosuperior mediastinum. CT findings of ectopic thyroid can be various and are dependent on several factors, such as its iodine content, the extent of tissue degeneration, and the presence of colloid cysts. This is a case of right...

ABSTR•CT.--Histological criteria indicate that thyroid glands are organized into follicles at about the same time of incubation in Japanese Quail (precocial) and Ringed Turtle Dove (altricial) embryos, but dove thyroids develop more slowly, are much smaller and are much less active than quail thyroids by the time of hatching. These results indicate thyroid readiness for participation in early e...

The aim of the study is evaluation of absorbed doses for thyroids by using neck phantoms. For this purpose, it was arranged the irradiation set with different phantoms. Three different materials were used for phantom materials as, water, paraffin and wood. The phantoms were three different dimensions for simulation of different ages and human race for each material. Co-60 gamma source was used ...