Coronary thrombosis and myocardial infarction It is a little over a decade since the acute management of myocardial infarction underwent a revolution with direct intervention on the coronary occlusive lesion. This approach had validity only if the coronary occlusion caused infarction. The evidence generated by coronary angiography soon after the onset of pain, the frequent restoration of corona...

Thrombotic microangiopathy (TMA) describes a pathological process of microvascular thrombosis, consumptive thrombocytopenia, and microangiopathic hemolytic anemia, leading to end-organ ischemia and infarction, affecting particularly the kidney and brain. TMA is a pathological feature of a number of clinical disorders including thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, and ...

UNEXPECTED CORONARY THROMBOSIS INDUCED BY ANTIPHOSPHOLIPID SYNDROME (HUGHES SYNDROME) CASE REPORT (Abstract): Antiphospholipid syndrome (APS), one of the most common states of acquired hypercoagulability, is diagnosed by the persistent presence of antiphospholipid antibodies and recurrent episodes of vascular thrombosis. We present the case of a 39-year-old man late-presenting for cardiac rehab...

Acute myocardial infarction had generally been considered to be the result of thrombotic occlusion of a major extramural coronary artery until postmortem observations of the infrequency of coronary thrombi began to accumulate in patients who died of extensive myocardial infarction. Roberts and Buja' found coronary artery thrombi in 40 (54%) of 74 patients with transmural necrosis, in none of 9 ...

The current clinical practice advocates dual antiplatelet therapy (DAPT) for a year after ST segment elevation myocardial infarction (STEMI), primarily owing to persistent thrombotic risk. novel COBRA PzF coronary stent was developed reduce thrombosis primary goal of the research compare efficacy and safety nanocoated stenting with one-month DAPT (dual anti-platelet therapy) against 12-month dr...

Acute myocardial infarction had generally been considered to be the result of thrombotic occlusion of a major extramural coronary artery until postmortem observations of the infrequency of coronary thrombi began to accumulate in patients who died of extensive myocardial infarction. Roberts and Buja' found coronary artery thrombi in 40 (54%) of 74 patients with transmural necrosis, in none of 9 ...

The coronary angiograms of 120 consecutive patients under 40 years of age were examined. Ten new cases of myocardial infarction with normal coronary arteriogram were identified (group 1) and compared with 30 cases of myocardial infarction and obstructive coronary disease (group 2). Heavy cigarette smoking was the sole major risk factor in group 1. Patients in group 2 smoked as well but most als...

Coagulation is triggered during the onset of myocardial infarction, resulting in vascular occlusion. However, a causal role for individual haemostatic factors in the development of thrombotic occlusion is not established. Three cases (all relatively young women) are reported of raised factor VIII associated with myocardial infarction. Two patients presented acutely with myocardial infarction at...

Coagulation is triggered during the onset of myocardial infarction, resulting in vascular occlusion. However, a causal role for individual haemostatic factors in the development of thrombotic occlusion is not established. Three cases (all relatively young women) are reported of raised factor VIII associated with myocardial infarction. Two patients presented acutely with myocardial infarction at...

Coronavirus disease (COVID)-19, especially the severe is associated with an increased risk and prevalence of venous thromboembolism [1]. Severe acute respiratory syndrome coronavirus (SARS-CoV-2) binds to angiotensin converting enzyme-2 (ACE-2) receptors on endothelial cells, within kidneys, heart, lungs, etc. causing cell damage leading thrombosis thrombotic complications like deep vein thromb...