Purpose: To study the effect of Cilostazol on rat thromboangiitis obliterans (TAO), and mechanism action involved.
 Methods: Rats (N = 45) were injected with sodium laurate to establish model TAO, then divided into Sham group (n 15), TAO 15) + cilostazol 15). After administration cilostazol, lesions in rats graded, femoral arteries stained by hematoxylin-eosin (H&E) determine degree va...

BACKGROUND This study aimed to determine the prevalence of genetic and environmental vascular risk factors in non diabetic patients with premature peripheral arterial disease, either peripheral arterial occlusive disease or thromboangiitis obliterans, the two main entities of peripheral arterial disease, and to established whether some of them are specifically associated with one or another of ...

A stroke due to vascular occlusion in a young person can raise many diagnostic and prognostic problems. In the following case report hemiplegia of sudden onset occurred in a young man followed by partial recovery without a definite diagnosis being made, despite full investigation. Further progression of the disease leading to death two years later enabled a complete pathological investigation t...

Thromboangiitis Obliterans is a non-atherosclerotic inflammatory disease of unknown etiology, which has a strong association with tobacco. We present current concepts on the pathophysiology and diagnosis, as well as a review in treatments.

Thromboangiitis obliterans or Buerger's disease is a segmental occlusive inflammatory condition of arteries and veins, characterized by thrombosis and recanalization of the affected vessels. It is a non-atherosclerotic inflammatory disease affecting small and medium sized arteries and veins of upper and lower extremities. The clinical criteria include: age under 45 years; current or recent hist...

Thromboangiitis obliterans (Buerger'€™s disease) represents an inflammatory disease of limbs'€™ small arteries and veins causing vascular thrombosis, and partial or total obstruction. It affects mostly male gender aged 40 years old. The peculiarity of our case is underlined by presenting a 62 years, chronic tobacco user and not compliant female patient known with thromb oangiitisobliterans for ...

Thromboangiitis obliterans (TAO), or Buerger's disease, is a vascular occlusive disease associated with cigarette smoking. It typically affects medium sized vessels of extremities. Basic pathology of TAO is described to be endothelial activation with highly inflammatory intraluminal thrombosis preserving internal elastic membrane. Cryoglobulins are immunoglobulins that precipitate in the cold a...