Between August 8, 1974, and November 1, 1978, calls reporting 100 cases of mushroom poisoning were received by the National Institutes of Health. Thioctic acid was sent (under IND # 9957) for the treatment of seventy-five of these patients thought to have ingested mushrooms containing alpha-amanitin. Sixty-seven patients recovered, and eight died. The lapse of time between ingestion of mushroom...

Welshimer, H. J. (Medical College of Virginia, Richmond). Vitamin requirements of Listeria monocytogenes. J. Bacteriol. 85:1156-1159. 1963.-Semidefined and completely defined media were used to determine the growth response of Listeria monocytogenes to several vitamins. All strains tested failed to grow for more than one or two passages in the absence of any one of the following vitamins: ribof...

If thioctic acid is an intermediate in photosynthesis closely related to the primary photochemical act as proposed by Calvin and Barltrop,I it should be possible to realize experimental conditions under which the concentration of thioctic acid limits the quantum efficiency of photosynthesis as well as the closely related Hill reaction. Conditions under which the amounts of thioctic acid and oxi...

Dopamine can be detected selectively in the presence of ascorbate at a gold electrode modified by a beta-cyclodextrin/thioctic acid mixed monolayer.

A sensitive sensor for the determination of hydrogen peroxide (H(2)O(2)) was fabricated by immobilizing cytochrome c (cyt c) on binary self-assembled monolayers (SAMs) of 5-(1,2-dithiolan-3-yl)valeric acid (thioctic acid, T-COOH) and 5-(1,2-dithiolan-3-yl)valeramide (thioctic acid amide, T-NH(2)) on gold electrodes. The electrochemical characteristics of immobilized cyt c were investigated by c...