The results of these studies indicate that a high percentage of Nebraska range cattle are infected with gastrointestinal parasites, but at a subclinical level of infection. However, significant differences were not observed in average daily gain between thiabendazole-treated range cattle and unmedicated controls in three of four field trials. In the three trials the average improvement in daily...

Thiabendazole, classified as antiparasitic and also used as an antifungal drug, can be found as otological solution indicated for treatment of parasitic and fungal external otitis in small animals. Malassezia pachydermatis is a yeast recognized as a normal inhabitant on the skin and mucous membranes of dogs and cats. However, it is considered an opportunistic agent that causes external otitis a...

Benzimidazoles are the most commonly used anthelmintic drugs for the chemical control of sheep strongylidoses in Bulgaria. The intensive and not always proper application could be able to cause a reduction of their efficacy. To establish benzimidazole resistances among gastrointestinal strongylids, two in vitro assays were performed – Egg Hatch Assay (EHA) and Larval Development Assay (LDA). Th...

Solid-phase extraction (SPE) procedures were developed for rapid cleanup and determination of thiabendazole and carbendazim in orange, apple, and grape juices. Samples were prepared by using an SPE cartridge containing a mixed-mode sorbent with both reversed-phase and strong cation-exchange chemistries. Analysis was by liquid chromatography with photodiode-array UV detection. Orange juice was a...

A case of Aspergillus flavus keratitis treated successfully with 4% suspension of thiabendazole is reported. This seems to be the first case of successful treatment of keratomycosis with thiabendazole. All other reported cases treated with this drug either had their eyes removed or did not retain any useful vision. Its ability to penetrate ocular tissues, ability to remain in concentrations hig...

A group of seven ponies naturally infected with large numbers of small strongyles and raised under conditions to minimize reinfection were treated periodically over a three year span with thiabendazole at the rate of 44 mg/kg body weight. Based on the absence of worm eggs in the feces following each treatment, thiabendazole removed the adult strongyles present with a new population subsequently...

Thiabendazole (TBZ) is a fungicide that is used for postharvest application to fruit and vegetables. It can also be mixed with paint to inhibit the growth of mildew. During 1982 to 1992, a total of 17 human illness/injury cases associated with exposure to TBZ were reported in California. Most of these cases were skin rashes that occurred following handling treated fruit in packing facilities. W...

BACKGROUND Strongyloidiasis is a gut infection with Strongyloides stercoralis which is common world wide. Chronic infection usually causes a skin rash, vomiting, diarrhoea or constipation, and respiratory problems, and it can be fatal in people with immune deficiency. It may be treated with ivermectin or albendazole or thiabendazole. OBJECTIVES To assess the effects of ivermectin versus benzi...