Background: One of the complications of the diabetes mellitus is the amputation of the lower limbs. This complication may be developed after an insidious ulcer, that may be raised by the peripheral neuropathy or the ischaemic limb, and that the ulcer get infected. That is, to develop an ulcer, in the diabetic patient, three factors should be taken into the account, the autonomic nervous system,...

Melanoma is the fifth most common cancer in United States and deadliest of all skin cancers. Even with recent advancements treatment, there still a 13% two-year recurrence rate, approximately 30% recurrences being distant metastases. Identifying patients at high risk for or advanced disease critical optimal clinical decision-making. Currently, substantial variability selection screening tests i...