background this prospective study was designed to examine the role of fibrosis staging on selection and success of treatment options for autoimmune hepatitis (aih). materials and methods the project was conducted on 110 selected aih patients who, based on the results of liver biopsy, had been assigned into one of the three groups (mild, stages 1 and 2, moderate, stages 3 and 4, and severe, stag...

this is a retrospective study on clinical course and treatment response of patients with thyroid hot nodule, referred to nuclear medicine department of shariati hospital from 1360 to 1377. from the total 58 patients with average age of 43 yr and incidence peak of 40 yr, 81% were female and 19% were male. 64% of the patients were thyrotoxic and 36% were euthyroid at presentation. thyrotoxic symp...

results patients who attained sustained virological response had a less risk (85%) for all-cause mortality and about 63% reduced risk of hepatocellular carcinoma incidence than those who did not achieve sustained virological response. based on deeply analysis, the stage of liver fibrosis was a risk factor at baseline for the incidence of hepatocellular carcinoma. conclusions sustained virologic...

This is a retrospective study on clinical course and treatment response of patients with thyroid hot nodule, referred to nuclear medicine department of Shariati Hospital from 1360 to 1377. From the total 58 patients with average age of 43 yr and incidence peak of 40 yr, 81% were female and 19% were male. 64% of the patients were thyrotoxic and 36% were euthyroid at presentation. Thyrotoxi...

conclusions this study supports the idea that the ifnl3 gene is an important predictor of the response of chb patients to ifn therapy. results nine studies of 1602 chb patients receiving ifn treatment were included. under the random-effects model, patients expressing the variant rs12980275 showed a significantly increased response to ifn therapy (or = 2.85; 95% ci = 1.14 - 4.60). in the subgrou...

hepatitis c virus is one of the main reasons for chronic liver disease and hepatocellular carcinoma. combination therapy with interferon (peg-ifn-α) and ribavirin (rbv) clear the virus more likely than the others. different factors like virus and host characteristics influence on response to treatment. the most important viral factors include virus genotype and viral load; host factors like gen...

background treatment with peginterferon alpha-2b plus ribavirin is the current standard therapy for chronic hepatitis c (chc). however, many host related and viral parameters are associated with different outcomes of combination therapy. objectives the aim of this study was to develop an artificial neural network (ann) model to predetermine individual responses to therapy based on patient’s dem...