background worldwide, the incidence of inflammatory bowel disease (ibd) is increasing. this study aims to evaluate the diagnostic value of two serological markers, atypical perinuclear anti-neutrophil cytoplasmic antibodies (atypical-p-anca) and anti-saccharomyces cerevisiae antibodies (asca), with the intent to determinetheir relationship to ulcerative colitis (uc) and crohn's disease (cd), in...

Background: Human CD34 is a transmembrane glycoprotein which is expressed in human hematopoietic stem cells (HSCs) and the small- vessel endothelial cells of a variety of tissues. CD34 plays a critical role as a marker for diagnosis and classification of leukemia. Anti CD34 antibodies are used for isolation and purification of HSCs from bone marrow, peripheral blood and cord blood. Objective: ...

Background: Decay of vaccine–induced antibody titres without boosting of the wild measles virus has been well documented. Revaccination against measles has reduced the prevalence of the disease worldwide. Revaccination may cause IgE induced anaphylaxis. Objective: To study measles IgG antibody in revaccinated populations and its relation to IgE induced hypersensitivity. Methods: Blood samples w...

Background: Inhibitory antibody to exogenous Factor VIII (FVIII) is a major complication of hemophilia treatment. This study was conducted to determine the prevalence of inhibitor antibody directed against FVIII.Methods: From May 2010 to May 2011, 52 patients with severe hemophilia A admitted in Amirkola Children’s Hospital were evaluated. Those who had abnormal mixing study, antibody against F...

objective: seeking for fertility after previous vasectomy is increasing. vasectomy may break the blood testis barrier and in this way the level of antisperm antibody increases. it is suggested that increase in antisperm antibody decreases spontaneous pregnancy even after successful vasovasostomy. in this study we evaluated antisperm antibody formation 3 months after vasectomy. method: this stud...

conclusions in this city, a great proportion of children are susceptible to hepatitis a and it’s complications at an older age. this decrease in seropositivity may be caused by elevated hygien level. according to our results hepatitis a vaccination is recommended at early childhood such as that of other regions where low prevalence of hepatitis a infection is found. patients and methods this cr...

in order to study the seroprevalence of pestivirus infection in small ruminants of ahvaz at khouzestan province of iran, 148 sheep sera and 143 goat sera were randomly collected and tested by seroneutralization. seroneutralization was performed by nadl strain of bovine viral diarrhea virus genotype 1. the results indicated the overall seroprevanelces of 46.62% in sheep and 32.871% in goats. pre...

patients with turner’s syndrome (ts) are at an increased risk of developing autoimmune thyroid disease (atd). the aim of this study was to determine the frequency of anti-thyroid peroxidase (anti-tpo) antibodies and atd in children and adolescent girls with ts. it also assessed the influence of karyotype on the development of thyroid disease. sixty eight patients with ts were compared with 68 a...

nutrition is an important factor that influences immunity, and nutritional deficiencies can impair resistance to infections. malnutrition is the most common cause of immunodeficiency worldwide. trace elements such as zinc, selenium, iron, and copper can influence several components of immunity. primary antibody deficiency disorders are a group of disorders characterized by an unusual susceptibi...

by immunizing mice with killed whole bacterial cells of brucella abortus s (99), a panel of six hybridomas producing monoclonal antibodies (mab) specific for the surface antigens of this bacterium were produced. elisa was used to screen the hybridoma supernatants. immunoblots of the cell extract indicated that three mab were specific for s-lps (ba-1, ba-2, ba-3) and three others were reactive w...