Introduction Low dose rate brachytherapy sources have been widely used for interstitial implants in tumor sites, particularly in prostate. Dosimetric characteristics of a new IrSeed 125I brachytherapy source have been determined using the LiF thermoluminescent dosimeter (TLD) chips. Materials and Methods Dose rate constant, radial dose function, and anisotropy function around the IrSeed 125I so...

Introduction: Brachytherapy is the use of small encapsulated radioactive sources in close vicinity of tumors. Various methods are used to obtain the dose distribution around brachytherapy sources. TG-43 is a dosimetry protocol proposed by the AAPM for determining dose distributions around brachytherapy sources. The goal of this study is to update this protocol for presence of bone and air inhom...

Purpose To perform a comparative study of heterogeneities and finite patient dimension effects in 60Co and 192Ir high-dose-rate (HDR) brachytherapy. Material and methods Clinically equivalent plans were prepared for 19 cases (8 breast, 5 esophagus, 6 gynecologic) using the Ir2.A85-2 and the Co0.A86 HDR sources, with a TG-43 based treatment planning system (TPS). Phase space files were obtaine...

The charge of Task Group 186 (TG-186) is to provide guidance for early adopters of model-based dose calculation algorithms (MBDCAs) for brachytherapy (BT) dose calculations to ensure practice uniformity. Contrary to external beam radiotherapy, heterogeneity correction algorithms have only recently been made available to the BT community. Yet, BT dose calculation accuracy is highly dependent on ...

BACKGROUND Since the term chronic allograft nephropathy (CAN) was removed from the Banff scheme in 2005, transplant glomerulopathy (TG) has been regarded as a clinicopathological entity that is one of the major causes of graft loss. To assess the distinction between CAN and TG, we performed a comprehensive evaluation comparing TG with traditional CAN. METHODS We compared the clinicopathologic...

Frontotemporal dementia (FTD) causes progressive personality, behavior and/or language disturbances and represents the second most common form of dementia under the age of 65. Over half of all FTD cases are classified pathologically as frontotemporal lobar degeneration (FTLD) with TAR DNA-binding protein of 43 kDa (TDP-43) pathology (FTLD-TDP). In FTLD-TDP brains, TDP-43 is phosphorylated, C-te...

Objective: Brachytherapy sources are widely used for the treatment of cancer. The report of Task Group No. 43 (TG-43) of American Association of Physicists in Medicine is known as the most common method for the determination of dosimetric parameters for brachytherapy sources. The aim of this study is to obtain TG-43 dosimetric parameters for 60Co, 137Cs, 192Ir and 103Pd brachyt...