Objective: Our country has limited data on protective antibody levels following primary tetanus immunization. In this study, we planned to evaluate the seroprevalence of healthcare workers in our hospital according age and occupational groups. Methods: Tetanus were determined by enzyme-linked immunosorbent assay (ELISA) method. Antibody results obtained through operating system, level ≥0.5 IU/m...

background and objectives: hiv infected patients are at risk for vaccine-preventable infections such as tetanus and diphtheria (td). in these patients, these antibodies tend to decline faster. due to the limited data, this study assessed the seroprevalence of tetanus and diphtheria antibodies in hiv infected patients in tehran, iran. materials and methods: this case-control study was carried o...

Vaccination effectiveness is proven when the disease does not develop after a patient is exposed to the pathogen. In the case of rare diseases, vaccination effectiveness is assessed by monitoring specific antibody levels in the population. Such recurrent analyses allow the evaluation of vaccination programs. The primary schedule of diphtheria and tetanus vaccinations is similar in various count...

background: light chain (lc) and heavy chain carboxyterminal subdomain (hcc) fragments are the most important parts of tetanus neurotoxin (tent) which play key roles in toxicity and binding of tent, respectively. in the present study, these two fragments were cloned and expressed in a prokaryotic system and their identity was confirmed using anti-tent specific polyclonal and monoclonal antibodi...

universal vaccination of neonates and children against diphtheria, tetanus and pertussis has had a tremendous impact on the control of these infectious diseases worldwide. immunization by the triple diphtheria, tetanus and whole cell pertussis vaccine (dtwp) has been applied in iran for almost 50 years. periodic assessment of immunogenicity of this vaccine is an important aspect of successful m...

In order to assess the effect of the neonatal tetanus elimination program in Turkey, tetanus antibody prevalence among women of childbearing age from three selected provinces was evaluated in relation to vaccination doses of the single-type tetanus vaccine. A combined method of in-house enzyme-linked immunosorbent assay and particle agglutination test was used to determine tetanus antibody tite...

Tetanus is a bacterial infection caused by Clostridium tetani and most commonly presents as trismus or other muscle spasms. Despite the development of the tetanus toxoid vaccine, tetanus infection has not been eradicated. Additionally, while there are hypothesized protective levels of tetanus antibody, tetanus infection may still occur in properly vaccinated individuals. We report the case of a...

BACKGROUND There is a noticeable difference in serologic immune status against tetanus among different age and social groups in various countries due to different national vaccination policies and methods. OBJECTIVES Considering that the immunization status of trauma patients against tetanus is not-known or uncertain and they may need to receive the vaccine and tetabulin, this study was condu...

Persistence of immune memory in humans is a crucial yet poorly understood aspect immunology. Here we have studied the effect Puumala hantavirus infection on unrelated, pre-existing by studying T cell- and antibody responses against toxoid vaccine antigens diphtheria, tetanus pertussis cohort 45 patients. We found that tetanus- -specific IgG concentrations elevate during acute virus infection. I...