Using testicular spermatozoa from either open biopsy (29 cycles) or biopty gun needle biopsy (49 cycles), a total of 81 intracytoplasmic sperm injection (ICSI) cycles among 57 couples were carried out from January, 1994 to September, 1997. In six cycles, no spermatozoa were obtained, and in three cycles spermatozoa from both needle and open biopsies were used. The fertilization (37% after open ...

background: about 10% to 15% of infertile men have azoospermia, which could be obstructive or non-obstructive. diagnostic biopsy from the testis and recently testicular sperm extraction (tese) are the most precise investigations in these patients. testicular biopsy can be done unilaterally or bilaterally. the worth of unilateral or bilateral testicular biopsy in men with azoospermia is controve...

251 Figure (A). Clinical picture shows left orchidectomy with enlarged right testes. (B) Testicular core biopsy showing uniform population of large cells with round nuclei, coarse chromatin and prominent nucleoli (Hematoxylin and Eosin, 40x). (C) Testicular core biopsy showing areas of necrosis and inflammatory infiltrate (Hematoxylin and Eosin, 40x). Testicular biopsy showing plasmablastic lym...

The aim of the study was to determine whether a prior diagnostic testicle biopsy can predict success or failure of testicular sperm extraction (TESE) with intracytoplasmic sperm injection (ICSI) in patients with non-obstructive azoospermia caused by testicular failure, and what is the minimum threshold of sperm production in the testis which must be surpassed for spermatozoa to reach the ejacul...

OBJECTIVE To study the outcomes of microdissection testicular sperm extraction (microTESE) among men with pure Sertoli cell-only histology on diagnostic testicular biopsy. DESIGN Retrospective cohort study. SETTING Tertiary referral center. PATIENT(S) Six hundred forty patients with pure Sertoli cell-only histology on testicular biopsy who underwent microTESE by a single surgeon. INTERV...

Azoospermia factor (AZF) region microdeletions, which account for about 10-15% of patients with oligoazoospermia, seem to lack a close genotype-testicular phenotype correlation. Although many genetic and non-genetic factors may contribute to this outcome, it was thought that a spontaneous regression of testicular germ cells might also play a relevant role. The opportunity for carrying out two d...

PURPOSE We aimed to evaluate the efficacy of using testicular biopsy histopathology as an indicator of the success of loupe-assisted subinguinal varicocelectomy in non-obstructive azoospermia (NOA) patients. MATERIALS AND METHODS In a 2-year period, a prospective study was carried at Minoufiya University Hospital on 20 NOA patients with clinical bilateral varicoceles. These patients underwent...

CONTEXT The combination of testicular biopsy and clinical evaluation for male infertility is becoming progressively more important because new technologies allow men previously considered infertile to father children. Although most general pathologists are experienced with normal, neoplastic, and cryptorchid testicular specimens, the testicular biopsy for infertility requires understanding of a...