PURPOSE To investigate the presence and the possible role of different matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in Tenon capsule fibroblasts. These enzymes are essential for the control of tissue remodeling in the context of wound repair. This aspect is important to further the understanding of and possibly to influence the scarring process of filtering blebs after g...

L aser suture lysis is commonly performed after trabeculectomy and is titrated to control postoperative flow through the filter to a target intraocular pressure. Originally, the flat edge of a Zeiss 4-mirror lens was used to compress the conjunctiva and Tenon capsule to view the sutures. The Hoskins lens designed for suture lysis improved the view and allowed eyelid elevation for better exposur...

PURPOSE For development of a finite element analysis model of orbital mechanics, it was necessary to determine the material properties of orbital fat and its degree of deformation in eye rotation. METHODS Elasticity and viscosity of orbital fat of eight orbits of four calves and two orbits of one rhesus monkey were measured with a parallel-plate rheometer. The degree of deformation of orbital...

1Nuclear Medicine Department, AP-HP Hôpital Tenon, Paris, France; 2Laboratoire IMNC–CNRS P7–P11, Paris, France; 3Gynecology Department, AP-HP Hôpital Tenon, Paris, France; 4INSERM, UMR S953, Epidemiological Research Unit on Perinatal Health and Women’s and Children’s Health, Hôpital Tenon, Paris, France; 5Université Pierre et Marie Curie Paris 06, UMR S 953, Paris, France; and 6Université d’Evr...

BACKGROUND/AIMS To devise and evaluate a novel Ocular Anaesthetic Scoring System (OASS) for non-topical local anaesthesia. METHODS In OASS, a score of between 0 (poor) and 14 (excellent) was devised measuring motor (ocular motility, levator and orbicularis function) and sensory functions (digital spear pressure at limbus and topical anaesthetic sting). 40 patients were studied prospectively t...

Biiagan, Hindu male, aged 35 years, was admitted to the Gaya Pilgrim Hospital with a tumour in the left orbital fossa. It had begun three years before, gradually increasing in size, and pushing the eyeball forwards. There was no history of syphilis or family history of importance. The eyeball, which was almost embedded in the growth, protruded from the orbital fossa forwards and outwards; visio...

PURPOSE The purpose of this study was to compare the level of patient pain during the phacoemulsification and implantation of foldable intraocular lenses while under topical, intracameral, or sub-Tenon lidocaine. PATIENTS AND METHODS This was a retrospective study. Three hundred and one eyes subjected to cataract surgery were included in this study. All eyes underwent phacoemulsification surg...

Since the introduction of gentamicin (given both as a soaked sponge and as an injection below Tenon's capsule at the end of surgery) no case of early infection either with or without intraocular signs after operation for retinal detachment has occurred in a series of 206 cases comprising 243 operations. However, late infection many months after operation has appeared in 3 cases (1-5%), though t...

BACKGROUND/AIM Mycophenolate mofetil could be a useful antiproliferative drug in glaucoma filtering surgery. In this study the authors set out to investigate whether growth inhibition of mycophenolate mofetil on human Tenon fibroblasts is mediated by guanosine depletion. METHODS Cultured human Tenon fibroblasts were incubated in various concentrations of mycophenolate mofetil with and without...