BMJ 1993;307:1326-9 Abstract Objectives-To study the prevalence of asthma (asthma symptoms and bronchial hyperresponsiveness) in Swedish cross country skiers compared with non-skiers and monitor changes in symptoms and bronchial hyperresponsiveness during the year. Design-Cross sectional study during the winter ski season and in the summer. Setting-Six ski clubs for 6lite skiers (total 47) in t...

Shifting flowering phenology with rising temperatures is occurring worldwide, but the rarity of co-occurring long-term observational and temperature records has hindered the evaluation of phenological responsiveness in many species and across large spatial scales. We used herbarium specimens combined with historic temperature data to examine the impact of climate change on flowering trends in 1...

mental disorders are known to be an important cause of disabilities worldwide. despite their importance, about two thirds of mentally ill people do not seek treatment, probably because of the mental health system's inability to decrease the negative side effects of the interaction with the mental health services. the world health organization has suggested the concept of responsiveness as a way...

The biophysical basis of temperature-sensitive ion channel gating has been a tough nut to crack. Chowdhury, et al. use a protein engineering approach to render a temperature-insensitive voltage-gated channel cold- or heat-responsive to reveal principles for temperature-gating and a plausible model for molecularly enabling this mode of environmental responsiveness.

We delivered controlled radio frequency energy to the airways of anesthetized, ventilated dogs to examine the effect of this treatment on reducing airway narrowing caused by a known airway constrictor. The airways of 11 dogs were treated with a specially designed bronchial catheter in three of four lung regions. Treatments in each of the three treated lung regions were controlled to a different...

The I28 immunoglobulin (Ig)-like module of human cardiac titin, an elastic muscle protein, was used to cross-link acrylamide (AAm) copolymers into hybrid hydrogels. Cross-linking was accomplished through metal coordination bonding between terminal histidine tags (His tags) of the I28 module and metal-chelating nitrilotriacetic acid (NTA)-containing side chains on the copolymer. In solution, the...

The responsiveness of murine lymphocytes and human peripheral blood lymphocytes to phytohemagglutinin, concanavalin A, pokeweed mitogen, and endotoxin was tested in vitro at 32, 35, and 37 degrees C. The responses at 32 degrees C were delayed and often depressed. Mouse cells responded equally well at 35 and 37 degrees C. Human lymphocytes often responded more rapidly at 37 than at 35 degrees C....

background:  assessment  of quality-of-life (qof) as  an outcome   measure   after  deep   brain  stimulation   (dbs) surgery in patients  with parkinson’s disease  (pd) need  a valid, reliable and responsive  instrument. the aim of the current   study   was   to   determine   responsiveness   of validated  persian  version  of pd questionnaire  with  39- items (pdq-39) after dbs surgery in pat...

admiration for environment in general needs to be profoundly rooted in an understanding of history. urban history is unique not only in the fact that it reflects climate but also in that it cuts across many different fields. in most schools of urban studies many aspects of science and technology are taught with relation to design in order to attain skills for practice. during a student’s later ...