Vekovima čovekova prirodna radoznalost za ljudsko telo dovodila je do stvaranja raznih instrumenata od kojih su mnogi slični današnjoj dijagnostičkoj opremi. Prvi veliki napredak u endoskopiji učinjen je u 19. veku. Filip Bocini (Phillip Bozzini, 1773–1809) opisao je 1806. godine instrument koji vizuelizuje unutrašnjost mokraćne bešike i nazvao ga lichtleiter . Okrugli otvor lichtleitera bio je...

0. Introduction The Modern Greek future marker [Ta] has long been recognized as deriving from an earlier, Medieval Greek formation based on the main verb ["Telo] ‘want’ used as an auxiliary (so Psicharis 1884, Meillet 1912, among others). The details of this development, however, are far from clear. Complicating the picture is the fact that a vast array of Medieval Greek future formations based...

Escherichia coli phage N15 encodes the slightly acidic, 630-residue protein of 72.2 kDa called protelomerase (TelN). TelN is a component of the N15 replication system proposed to be involved in the generation of the linear prophage DNA. This linear DNA molecule has covalently closed ends. The reaction converting circular plasmids into linear molecules was catalyzed in vitro. We demonstrate that...

Introduction In November 2006, a diverse group of telomere researchers gathered in Madrid to celebrate two high-profile recognitions. First, the 2003 Josef Steiner Cancer Research award to Maria Blasco allowed her to organize this Cancer Conference with the help of Jerry Shay. Blasco was honoured for her contributions to our understanding of the connections between telomere function and cancer ...

Experimental studies are prevalent in Evolutionary Computation (EC), and concerns about the reproducibility replicability of such have increased recent times, reflecting similar other scientific fields. In this article, we discuss, within context EC, different types suggest a classification that refines badge system Association Computing Machinery (ACM) adopted by ACM Transactions on Learning O...

Background—Gradual telomere erosion eventually limits the replicative life span of somatic cells and is regarded as an ultimate tumour suppressor mechanism, eliminating cells that have accumulated genetic alterations. Telomerase, which has been found in over 85% of human cancers, elongates telomeres and may be required for tumorigenesis by the process of immortalisation. Malignant mesothelioma ...

PURPOSE Indicators of aging such as disruption of telomeric function due to shortening may be more frequent in dysfunctional lacrimal gland. The aims of this study were to 1) determine the viability of quantitative fluorescence in situ hybridization of telomeres (telo-FISH) for the assessment of telomere length in lacrimal gland in Sjögren and non- Sjögren syndrome patients; and 2) investigate ...