Bone scintigraphy has some limitations in detecting bone lesions at the time of diagnosis since Tc99m MDP scintigraphy does not trace lesions lacking osteoblastic activity3. Tc99m Sestamibi (MIBI) has been proposed as a potential tracer in patients with multiple myeloma, as its increased uptake in the bone marrow has been reported as an indicator of myeloma activity4. It has been suggested to b...

OBJECTIVE To determine the frequency of the types of parathyroid gland hyperplasia and the sensitivity of sestamibi-(99m)Tc (MIBI) scintigraphy and ultrasonography (US) of patients with secondary hyperparathyroidism (SHPT) due to chronic renal failure. MATERIAL AND METHODS We studied 43 patients with SHPT (26 females and 17 males with age range of 27-75 years). Blood tests were performed to d...

osteitis fibrosa cystica is the classic patognomonic form of skeletal disease in hyperparathyroidism that characterizes with decreased cortical bone thickness compared to increased cancellous bone. we present a case of 52-year old female patient with osteolysis of the left calf on radiographic images. the bone scan detected multiple focal pathological accumulations in the skull, left tibia, bot...

A 37-year-old male with a persistent increased parathyroid hormone level, after subtotal thyroidectomy and parathyroidectomy, was referred for scintigraphic localization of a possible ectopic parathyroid adenoma. Tc-99m pertechnetate and Tc-99m MIBI scintigraphy were performed on separate days. There was marked uptake of both tracers in the mediastinum, which at surgery was confirmed to be an e...

UNLABELLED The aim of this study is to assess the sensitivity of Tc-99m-MIBI for the pre-operative localization of hyperfunctioning parathyroid glands in patients with persistent or recurrent hyperparathyroidism (HPT) after total parathyroidectomy (PTX) with autograft. PATIENTS AND METHODS Tc-99m-MIBI scintigraphy was performed on 7 patients (3 men and 4 women; aged 32 to 62) on hemodialysis ...

UNLABELLED Surgical neck exploration is usually made in primary hyperparathyroidism (PHPT). Localization of the adenoma or detection of hyperplasia may reduce the operation period and limit the extent of the surgery. In this study the effficacy of preoperative Tc-99m MIBI scintigraphy and intraoperative gamma probe was evaluated. MATERIALS AND METHODS Six patients with PHPT had preoperative T...

Objective: The purpose of the present study was to evaluate the accuracy of double phase Tc sestamibi scintigraphy in the assessment of parathyroid glands in patients with hyperparathyroidism and to compare this method with the high-resolution ultrasonography. Methods: From August-1998 through August-2000, we performed Tc -MIBI scintigraphy (MIBI) and neck ultrasonography in 35 patients who wer...

The intrathyroidal parathyroid adenomas (IPA) represent a rare cause of primary hyperparathyroidism whose location difficults appropriate surgical removal. We present the case of a patient diagnosed of parathyroid adenoma by presurgical scintigraphy in which finally during the parathyroidectomy, the lesion location was intrathyroidal. We consider that the intrasurgical parathyroid scintigraphy ...

We report the case of a 64-year-old woman who had a severe hypercalcemia. Serum calcium, intact parathyroid hormone (PTH), 1alpha, 25 (OH)(2 )vitamin D(3) levels were all elevated, and serum phosphorus level was decreased, which were all consistent with primary hyperparathyroidism (PHPT). (201)Tl/(99m)Tc subtraction scintigraphy failed to detect any abnormal accumulation in the neck and chest, ...

Received 10/30/2002; revised 11/19/2002; accepted 12/16/2002. For correspondence or reprints contact: Hatice Uslu, M.D., Department of Nuclear Medicine, Medical School, Atatürk Universty, 25240 Erzurum, Turkey. Tel: 90-442-236-09-00, Fax: 90-442-236-08-84, E-mail: [email protected] Backgrounds: Tl/Tc-pertechnetate subtraction scintigraphy is recognized as a useful procedure in the preoperat...