Background: There are eight Taxus species and two hybrids in the world and Taxus baccata L. (European yew) is the single representative in Iran. Until now, a large number of taxoids possessing different skeleton systems, as well as lignans, flavonoids, steroids and sugar derivatives have been isolated from various Taxus species. Taxoids are highly oxygenated diterpenes isolated from different...

Four lignan type compounds, lariciresinol, taxiresinol, isolariciresinol and 3-demethyl-iso-lariciresinol, were isolated from the heartwood of Taxus baccata L. (Taxaceae) growing in Turkey through chromatographic techniques. In vivo anti-ulcerogenic potency of these compounds was investigated on ethanol-induced ulcerogenesis model in rats at two different doses, 50 and 100 mg/kg. All compounds ...

CONTEXT Taxine-derived alkaloids, taxane-derived substances, and glycosides seem to be responsible for the toxicity of Taxus spp. by blocking microtubule, sodium and calcium channels causing conduction abnormalities. Cases with Taxus baccata acute intoxication have rarely been reported. CASE DETAILS We report the case of a 43-year-old man who ingested, for suicidal purposes, common (or Europe...

background: taxol is one of the most important anti-cancer drugs, which is obtained from yew trees (taxus sp.). t+he fist step in side chainassembly of taxol is catalyzed by phenylalanine aminomutase, which converts α-phenylalanine to β-phenylalanine.objectives: in this study, for the fist time, we report on the cloning, preliminary expression and characterization of a full-length gene andcdna ...

Plants are rich source of natural products used for centuries to cure various the plant-derived medicines are based upon the premise that they contain natural substances that can promote health and alleviate illness. Silver NPs represent material, which can be used as a potential antibacterial agent in medical applications and different commercial products due to its biological activity. Recent...

Taxus baccata L. (Porsuk ağacı), ülkemizde populasyonu azalmakta olan ve yer korunmaya alınmış değerli bir ağaçtır. Genel olarak gölgeli korunaklı kuzey bakılarda serpili görülür. Mustafakemalpaşa Karacabey ilçelerinde yamaç araziler dere içlerinde küçük popülasyonlara bireylere sahip T. Bursa florası için önemli doğal tıbbi bitkilerdendir. Bu çalışmada araştırma yapılan ilçelerdeki porsuk ağac...

Twenty-eight leaf and twig samples and one bark sample of Taxus baccata from the Ukraine (Crimea), Russia, and Georgia were analyzed for taxane compounds. Taxol and the related diterpenoid I 0-deacetylbaccatin III (baccatin Ill) were present in all samples and 20.7% of those samples exhibited a taxol content nearly equal to or greater than that obtained from the bark of the Pacific Yew, T. brev...

A cladistic analysis of the medicinal plant Taxus, using the sequences of one chloroplast (trnS-trnQ spacer) and three nuclear taxadiene synthase (TS), 10-deacetylbaccatin III-10beta-O-acetyltransferase (DBAT), and 18S rDNA) molecular markers, was carried out by distance, parsimony, likelihood, and Bayesian methods. Three of the four New World species (T. brevifolia, T. floridana and T. globosa...