Kapova Cave (Shulgan-Tash) is located in Bashkortostan, the Southern Urals, in the Shulgan Tash Reserve on the Belaya River. Its coordinates are 53°02’ N; 57°03’ W. It is a large karst three-level system of chambers, galleries and wells having the total length of 3323 m with vertical amplitude of 165 m. The karst system is characterized by large chambers and galleries, great dynamics of microcl...

BACKGROUND The signal peptide for human B-type natriuretic peptide preprohormone (BNPsp), which is released from cardiomyocytes, is increased in plasma of patients with acute myocardial infarction (AMI); however, its exact release kinetics have not been defined. METHODS We measured BNPsp and high-sensitivity cardiac troponin T (hs-cTnT) in a reference group of individuals without structural h...

BACKGROUND The release kinetics of cardiac troponin T measured with conventional vs high-sensitivity cardiac troponin T (hs-cTnT) assays in patients with acute myocardial infarction (AMI) is difficult to establish. METHODS We analyzed the release kinetics of cTnT measured by fourth generation and high-sensitivity assays, creatine kinase-MB (CK-MB), and myoglobin in patients with hypertrophic ...

OBJECTIVE The aim of this study was to compare the hearing results of embedding the partial ossicular reconstruction prosthesis (PORP) underneath the malleus with the malleus relocation technique and tympanic membrane graft in the presence of the malleus. MATERIALS AND METHODS A retrospective review of patient charts and audiometric results in a tertiary referral center was conducted. In tota...

OBJECTIVES Our purpose is to validate previously described massive transfusion (MT) scoring in our Transfusion Trauma Registry. DESIGN A retrospective cohort of adult trauma patients. SETTING Trauma and Emergency Intensive Care Unit of a tertiary hospital. PATIENTS Patients with severe trauma (injury severity score>15) admitted from October 2006 to July 2009. INTERVENTIONS None. VARIA...

BACKGROUND Transcoronary ablation of septal hypertrophy (TASH) for hypertrophic cardiomyopathy seems to be an effective alternative to surgical myectomy. It remains a point of debate whether an outflow obstruction at rest is a necessary criterion for interventional therapy. METHODS AND RESULTS TASH was compared in 45 consecutive patients with no resting gradient and a provocable gradient of >...

BACKGROUND Prediction of massive transfusion (MT) is challenging in management of trauma patients. However, MT and its prediction were poorly studied in obese patients. The main objective was to assess the relationship between obesity and MT needs in trauma patients. The secondary objectives were to validate the Trauma Associated Severe Hemorrhage (TASH) score in predicting MT in obese patients...

BACKGROUND AND OBJECTIVES The empiric use of a high plasma to packed red-blood-cell [fresh frozen plasma:red-blood-cells (FFP:RBC)] ratio in trauma resuscitation for patients with massive bleeding has become well accepted without clear or objective indications. Increased plasma transfusion is associated with worse outcome in some patient populations. While previous studies analyse only patients...

Kapova Cave (Shulgan-Tash) is located in Bashkortostan, the Southern Urals, in the Shulgan Tash Reserve on the Belaya River. Its coordinates are 53°02’ N; 57°03’ W. It is a large karst three-level system of chambers, galleries and wells having the total length of 3323 m with vertical amplitude of 165 m. The karst system is characterized by large chambers and galleries, great dynamics of microcl...

Kapova Cave (Shulgan-Tash) is located in Bashkortostan, the Southern Urals, in the Shulgan Tash Reserve on the Belaya River. Its coordinates are 53°02’ N; 57°03’ W. It is a large karst three-level system of chambers, galleries and wells having the total length of 3323 m with vertical amplitude of 165 m. The karst system is characterized by large chambers and galleries, great dynamics of microcl...