We determined the effects of yolk water-soluble protein (YSP) on bone resorption. YSP potently suppressed osteoclastogenesis from bone marrow-derived precursor cells driven by tumor necrosis factor-alpha (TNF-alpha). YSP (200 microg/ml) abolished the formation of tartarate-resistant acid phosphatase (TRAP)-positive osteoclasts. Furthermore, TNF-alpha induced TRAP activity was greatly inhibited ...

Kumbakonam Hospital with the characteristic disease. Duration?six months. 23rd October, 1916, 2 ounces of a solution of antimony tartarate (1 erain in 2 oz. of distilled water) was given intravenously. Two days afterwards the surface showed signs of healing. On 30th October, 1916, my house surgeon gave another injection of the same strength. The patient is said to have left the hospital on 25tl...