نتایج جستجو برای: t2d
تعداد نتایج: 3280 فیلتر نتایج به سال:
Despite the valuable results achieved in identification of genes and genetic changes associated with type 2 diabetes (T2D), lack of consistency and reproducibility of these results in different populations is one of the challenges lie ahead in introduction of T2D candidate genes. Therefore, the present review article aimed to provide an overview of the most important genes and genetic variation...
Background: Perilipins are proteins at the external level of the lipid glob in adipocytes steroid-generating cells and play a central role in lipid storage and breakdown. FTO gene is associated with Type-2 diabetes (T2D) and increased fat mass. Association of Perilipin and FTO genes polymorphism with T2D was investigated. Methods: Clinical traits in a random sample of 183 Iranian men and wom...
b a ckground: type 2 diabetes (t2d) is an increasing public health problem primarily because of increase in the prevalence of a sedentary lifestyle and obesity. the aim of this study was to evaluate the efficacy of self-management education on metabolic control in adults with t2d. m ethods : in a quasi-experimental study, 300 patients with t2d recruited from the diabetes society of nat...
OBJECTIVE Shared genetic variants in ADIPOR1 have been identified as closely related to coronary artery disease (CAD), type 2 diabetes (T2D), and T2D with CAD susceptibility, suggesting that these variants are strong candidates for the common soil hypothesis. Therefore, it is essential to analyze the relationship between ADIPOR1 variants and the susceptibility to CAD, T2D, and T2D with CAD in o...
background and objectives: there is convincing evidence that subjects concomitantly affected by type 2 diabetes (t2d) and metabolic syndrome (mes) are at greater risk for cardiovascular disease (cvd). many metabolic derangements in t2d might be attributed to poor vitamin d status. the purpose of this study was to investigate the associations among vitamin d status, mes and glycemic status in su...
Background: Chronic inflammation has critical role in Type 2 diabetes (T2D), in which IL-1β contributes in insulin resistance and beta cell dysfunction. The activation of NLRP3 and AIM2 by endogens ligands, such as mtDNA can lead to the release of active form of IL-1β. Objective: To evaluate AIM2 expression and activation as well as circulating mtDNA levels in T2D patients. Methods: AIM2 expres...
Introduction: Biomarkers would significantly improve the early detection of the disease and identification of individuals at risk of emerging complications. Diabetes mellitus is a group of diverse and complex metabolic disorders. Both type 1 diabetes (T1D) and type 2 diabetes (T2D) mellitus are associated with distinct alterations in the profile of MicroRNAs (miRNAs) in the blood, which are som...
Type 2 diabetes (T2D) was first noted in Indigenous pediatric populations the early 1980s. children are disproportionately affected, experiencing higher rates of adverse outcomes than with type 1 or adults T2D. Nurse practitioners must manage screening, diagnosis, and treatment T2D among youth living remotely.
BACKGROUND This study evaluated the measurement properties of a newly developed instrument - the Self-Management Profile for Type 2 Diabetes (SMP-T2D). METHODS The 18-item SMP-T2D assesses 12 constructs: level and perceived ease of performance in five self-care domains (blood glucose monitoring, medication-taking, healthy eating, being physically active, and coping), and two global constructs...
background: the transcription factor 7-like 2 gene (tcf7l2) is an element of the wnt signaling pathway. there is lack of evidence if tcf7l2 has a functional role in lipid metabolism and regulation of the components constitutes the metabolic syndrome (metsyn).the aims of this study were to evaluate whether the risk allele of tcf7l2 gene polymorphism is associated with dyslipidemia and metsyn. ma...
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