peripheral blood t lymphocytes and their subsets were studied in 31 patients with beta thalassemia major (age 2-12years) and compared with 14 age-arid sex-matched healthy controls. three monoclonal antibodies (anti-cd3, anti cd-f, unti-cds) were simultaneously applied for detection of th (cd3-, cd4^), tsk (cd3+, cd8+) and th/ts ratio by flow-cytometry respectively. the results of this study sho...

multiple sclerosis (ms) is a complex neurological disease and its prevalence is about 2 million in the world. neuroinflammation plays a key role in ms. vitamins are essential nutrients that have effective role on immune system including activation of lymphocyte and differentiation of t-helper cell. vitamin d is a micronutrient that is effective on immune function. deficiently of vitamin d is a ...

a central role for t cells and their cytokines in the pathogenesis of psoriasis has been proposed; however, there are controversies over the details of this issue. the goal of this study is to summarise currently available data on the importance of t cells in psoriasis pathogenesis. a  systematic  review  of  the  english  medical  literature  was  conducted  by  searching pubmed, embase, isi w...

we report a case of a. naeslundii bacteremia in an 11 year-old boy with persistent fever for two weeks prior hospital admission. he was finally diagnosed with malignant t cell lymphoma. isolation of this bacterium from the blood culture of our patient can serve as an important warning indicating that incuriosity about fastidious and not easily grown bacteria isolated from clinical samples may l...

in spite of their key role in various immunological processes occurring in the endometrium, t cells- especially + subtype- residing in this mucosal tissue, have not been extensively explored. we present here the profile of expressed genes for variable region of chain of t cell receptor (tcr) in normal endometrium as compared to peripheral blood. samples from endometrium were taken from norm...

t cell acute lymphoblastic leukemia (all) is an invasive disease with a higher incidence in children and adolescents. in terms of immunophenotype, t-all is positive for cd2, cd7, cd34 and hla-dr, and the level of these markers is increased with increasing age. in addition, the myeloid markers (cd13, cd33) are sometimes expressed in t-all. in this study, we introduce a rare case of a 28-year-old...

background the effect of pyocyanine pigment, which was isolated and purified from pseudomonas aeruginosa, on specific lymphocytes viability inside the body of white male balb/c mice against the experimental secondary hydatidosis and the infectivity of protoscolices was studied in comparison with negative control mice groups, phosphate buffered saline (pbs) and positive control group (immunofero...

Background: Adipose derived stem cells (ASCs) provoke the accumulation and expansion of regulatory T cells, leading to the modulation of immune responses in tumor microenvironment. Objective: To assess the effect of tumoral ASCs on the trend of regulatory T cells differentiation. Methods: Peripheral blood naïve CD4+ T cells were co-cultured with ASCs derived from breast cancer or normal breast ...