in the present study, the diversity of trichoderma spp. was investigated in alkaline pistachio soils at different geographic area in kerman province, iran. a total of 161 trichoderma isolates were obtained and identified at the species level by analysis of their morphological characters and sequence analysis of their internal transcribed spacer regions of the rrna cluster and tef1 genes as phyl...

Three strains of Trichoderma brevicompactum and another four that are closely related to that species (Trichoderma cf. brevicompactum) were analyzed for the formation of polypeptide antibiotics (peptaibiotics) by LC/ESI-MS(n). These isolates were selected because of an antagonistic potential against Eutypa dieback and Esca disease of grapevine and have not yet been investigated for the producti...

Mycophenolic acid (MPA) is the active ingredient in the increasingly important immunosuppressive pharmaceuticals CellCept (Roche) and Myfortic (Novartis). Despite the long history of MPA, the molecular basis for its biosynthesis has remained enigmatic. Here we report the discovery of a polyketide synthase (PKS), MpaC, which we successfully characterized and identified as responsible for MPA pro...

genus trichoderma is a monophyletic fungus which some their species is known as biocontrol agent. this study was carried out for phylogenetic analysis of some isolates of the genus trichoderma. in this study 73 sequences (including 33 sequences from t. aspereluum, t. brevicompactum, t. capillare, t. harzianum, t. koningiopsis, t. pleuroticola and t. virens and 40 sequences obtained from geneban...

(Received: Feb. 24, 2013; Accepted in Revised Form: April 9, 2013) Abstract: Mycophenolic acid (MPA) is an antibiotic and immunosuppressive agent, as a secondary metabolite of Penicillium brevicompactum. Parameter optimization of culture composition using Test plan L16, available in the form of an orthogonal array and software for automatic design and analysis of the experiments, both based on ...

Domateste Fusarium oxysporum f.sp. lycopersici (FOL)’nin hastalık oluşturmasını engellemeye yönelik olarak yürütülen bu çalışmada, domates rizosferinden 29 fungus türü izole edilmiştir. Aspergillus ve Penicillium türlerinin hepsi in vitro’da FOL’ün miseliyal gelişmesini değişen oranlarda engellemişlerdir. Bu fungusların PDA besi yerinde inhibisyon zonu oluştururken bazıları gelişmeyi engelleyic...