Background & Aims: Diabetes is the most common cause of renal insufficiency throughout the world. The main cause of renal failure in diabetic patients is microvascular endothelial injuries that is secondary to atherosclerosis and ischemia. The efficacy of renal Doppler indices such as resistive index (RI) and pulsetile index (PI) for the evaluation of intrarenal arteries has been shown. This st...

T cell infiltration in the tumor microenvironment (TME) is positively correlated with survival. Infiltration is not a stable state, but a dynamic process of homing, infiltration, retention and survival. Every step in this process is crucial for the eventual tumor reactive activity of T cells. Our laboratory has previously shown a marked upregulation of retention integrins (RI) CD49a, CD49b and ...

From the coordinates transformation, we can see that only after i 1 (ri 1 (t)) is obtained can hi (ri (t )) be obtained. After we obtain hi (ri (t )) ; ~ ij (rj (t )) can be determined from (6). In other words, ~ ij (rj (t )) can not be determined until i 1 (ri 1 (t)) is obtained. However, from the iterative procedure in the main result of [1], we can see that function i 1 (ri 1 (t)) is obtaine...

Introduction: Primary percutaneous coronary intervention (PPCI) is used for the treatment of ST segment elevation myocardial infarction (STEMI). Anterior STEMI is associated with adverse outcomes, and it is possible that the presence of ramus intermedius (RI) would inversely affect the outcome. This research involved the evaluation of the influence of RI presence on clinical ou...

Maternal effects on offspring phenotypes occur because mothers in many species provide an environment for their developing young. Although these factors are correctly "environmental" with respect to the offspring genome, their variance may have both a genetic and an environmental basis in the maternal generation. Here, reciprocal crosses between C57BL/6J and 10 LGXSM recombinant inbred (RI) str...

The factor(s) regulating the combination of traits that define the overall life history matrix of mammalian species, comprising attributes such as brain and body weight, age at sexual maturity, lifespan and others, remains a complete mystery. The principal objectives of the present research are (1) to provide evidence for a key variable effecting life history integration and (2) to provide a mo...

The immune system plays a pivotal role in the susceptibility to and progression of a variety of diseases. Due to a strong genetic basis, heritable differences in immune function may contribute to differential disease susceptibility between individuals. Genetic reference populations, such as the BXD (C57BL/6J × DBA/2J) panel of recombinant inbred (RI) mouse strains, provide unique models through...

Printz, Morton P., Martin Jirout, Rebecca Jaworski, Adamu Alemayehu, and Vladimir Kren. Invited Review: HXB/BXH rat recombinant inbred strain platform: a newly enhanced tool for cardiovascular, behavioral and developmental genetics and genomics. J Appl Physiol 94: 2510–2522, 2003; 10.1152/japplphysiol.00064.2003.—This review deals with the largest set of rat recombinant inbred (RI) strains and ...

This report provides technical details missing from the INFOCOMM ‘02 paper [1]. The details are related to the design and analysis of the control system. 1 Model Our starting point is the fluid-flow model developed in [2] for modeling TCP flows and AQM routers. In this section we will extend this model to account for two-color marking at the network edge and multi-level active queue management ...