*Corresponding author: Pro. Mohammad-Reza Ardalan, Chronic Kidney Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. E-mail: [email protected] Implication for health policy/practice/research/medical education: Erythropoietin treatment could augment the immune response and could be a tiger for systemic lupus erythematous flare-up and increasing the activity of renal ...

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Cytomegalovirus (CMV) infection have been described as exacerbing systemic lupus erythematous (SLE). The role of CMV in starting off SLE remains object of debate. We report a severe presentation of SLE revealed by CMV infection with hemophogocytic syndrome. A 22 old women without a history of systemic disease developed a cutaneous eruption with fever and myalgia persistant for 2 weeks. Laborato...

Results A total of 59 patients, 49 (89%) were female and10 (16.9%) male. The female to male ratio was 4.9:1. The mean age of onset was 10.5 years (range 2-16). The mean duration of disease from diagnosis was 2 years (range7 months-5 years). The most common of constitutional sign was fatigue (76.3%) and the other signs were fever (32.2%), Nocturnal pain (20.3%), Mood disorder (20.03%), and Weigh...

Vasculitis are a heterogeneous group of disorders characterized by inflammation of the blood vessels of different caliber and sometimes fibrinoid necrosis with vessel wall destruction [1]. Vasculitis are divided into cutaneous and systemic forms, primary and secondary to hypertension, immunosuppression therapy, metabolic complications. The classification is based on the affected vessel size (Ta...

systemic lupus erythematous (sle) is an autoimmune process in which cutaneous lesions occur in majority of patients. this study was conducted to determine the pattern and prevalence of such lesions in sle in iranian children infected with sle. forty-eight patients, age between 3-16 yrs and male to female ratio of 7/1 were examined for the presence of cutaneous manifestations of sle. the most co...

Introduction: There are debates about the role of X-ray repair cross-complementation group 1 (XRCC1) Arg399Gln gene in pathogenesis Systemic Lupus Erythematosus (SLE). Methods: The study was a case-control carried out on 100 recently diagnosed SLE patients compared to control subjects. XRCC1 polymorphism performed by polymerase chain reaction and restriction fragment length polymorphism. Result...

We report a case of bilateral lupus Choroidopathy and central nervous system (CNS) vasculitis in a 43-year-old female with systemic lupus erythematous. The patient improved systemically on high dose steroids and mycophenolate. Choroiditis flared and escalation of therapy with Rituximab achieved CNS disease control. Choroiditis refractory to systemic therapy improved with micropulse laser therap...

Few patients with systemic lupus erythematosus have features of verrucous (hypertrophic) lupus erythematosus. A 29-year-old Caucasian woman with a 7-year history of systemic lupus erythematosus developed painful verrucous plaques on the nose. Erythematous, raised, indurated, hyperkeratotic plaques localized on the dorsa of the distal parts of the toes and over the interphalangeal joints of her ...