Synthetic polymers have transformed society in many areas of science and technology, including recent breakthroughs in medicine. Synthetic polymers now offer unique and versatile platforms for drug delivery, as they can be "bio-tailored" for applications as implants, medical devices, and injectable polymer-drug conjugates. However, while several currently used therapeutic proteins and small mol...

A large number of both natural and synthetic polymers have been studied for powible application in drug delivery. The great advantage of synthetic polymers is their advantageous properties and wide choice availability. Two promising synthetic polymers which have been developed for biomedical applications are polyvinylpyrolidone and polyethylene glycol acrylate based hydrogels. Both of them are ...

INTRODUCTION Extensively used polymers in biomedical applications are naturally occurring or synthetic compounds consisting of large molecules obtained from linking of simple monomers. Potential biomedical applications of these polymers include carrier based drug delivery systems, tissue engineering scaffold and cell culture supports [1]. Polymer based drug delivery system can control the rate ...

Biodegradable materials are used in packaging, agriculture, medicine and other areas. In recent years there has been an increase in interest in biodegradable polymers. Two classes of biodegradable polymers can be distinguished: synthetic or natural polymers. There are polymers produced from feedstocks derived either from petroleum resources (non renewable resources) or from biological resources...

Paliperidone is a well known dopamine antagonist of the atypical antipsychotic class. In the present study Paliperidone was formulated as ER release tablets using natural and synthetic polymers separately or in combination. The aim of ER release formulation is to reduce the frequency of dosing. Tablets are prepared by direct compression method. The optimized formulations contain Paliperidone as...

      Mucoadhesive polymers that bind to the gastric mucin or epithelial cell surface are useful in drug delivery for the purpose of increasing the intimacy and duration of contact of drug with the absorbing membrane. Several synthetic polymers are in use for this purpose. Since the biodegradability of the synthetic polymers are questionable, in this investigation, an oral mucoadhesive controll...

This paper reviews the application of matrixassisted laser desorption/ionization mass spectrometry (MALDI-MS) to the analysis of synthetic polymers, and includes data obtained by Toyota CRDL. In MALDI-MS of synthetic polymers, the selection of a matrix and cationizing agent, as well as the sample preparation techniques, are very important to obtaining a successful spectrum. MALDI-MS makes it po...

In this study, synthetic sulfonated polymers were used in order to enhance the rheological properties of drilling fluids. The capability of these polymers in reducing the effects of environmentally friendly, but harmful, pollutants such as cement, calcium chloride, gypsum as well as pH changes were investigated. In the present work, two sulfonated synthetic polymers, namely Polythin and Polydri...