Tactile stimulation (light stroking) of a body wall flap attached to the ventral nerve cord of the medicinal leech evokes episodes of swimming activity. This swimming response undergoes habituation, involving changes in swim initiation and swim maintenance. Repeated stimulation of the body wall flap evoked swimming activity between three and 39 times before this response failed. During repetiti...

introduction: the formalin test is the most accepted chemical test for evaluation of nociception. it requires the injection of an adequate amount of formalin into the surface of the hindpaw. formalin test consists of phase 1 (0-7 min) and phase 2 (15-60) in which the animal shows painful behaviors. these phases are separated with a quiet phase named interphase, in which the nociceptive response...

Background: In the present study, we aimed to clarify impact of Assisted swim (A-swim; towing from propulsion direction) on front crawl performance at maximum and sub-maximum effort levels. Methods: Fourteen male collegiate swimmers (age, 21.0 ± 2.0 years; height, 1.73 0.05 m; weight, 67.1 7.1 kg) participated. Participants swam 25-m maximal (Max) submaximal intensity (Submax (80% max stroke ra...

Introduction: In this study, we investigated whether neurofeedback (NFB) training and swimming exercise would decrease the electroencephalographic (EEG) changes visual image-induced craving in methamphetamine (METH)-dependent patients. Methods: This study was a randomized controlled trial design. 32 METH-dependent patients were allocated randomly to four groups; control, NFB, Swim, NFB/Swim. Th...

Introduction: Sub-chronic swim stress is known to induce a prolonged hyperalgesia, which is mediated through NMDA and opioid systems. Nitric oxide is a soluble gas, which acts as a retrograde messenger that modulates the release of mentioned neurotransmitters. It is also involved in nociception and memory. The aim of this study was to evaluate the role of NO pathway in nociception and memory...

Stress and chronic pain have been shown to prevent the development of tolerance to morphine analgesia, which appears to be related to neuroendocrine activity and alternation in neurochemicals. Also the involvement of nitric oxide (NO) has been implicated in tolerance to morphine analgesia. In our pervious study, we showed that co-administration of swim stress (ss) with chronic morphine, prevent...

Closely related species can exhibit different behaviours despite homologous neural substrates. The nudibranch molluscs Tritonia diomedea and Melibe leonina swim differently, yet their nervous systems contain homologous serotonergic neurons. In Tritonia, the dorsal swim interneurons (DSIs) are members of the swim central pattern generator (CPG) and their neurotransmitter serotonin is both necess...