A new detection mechanism has been developed for low molecular weight substrate binding to heme proteins based on resonance localized surface plasmon spectroscopy. Cytochrome P450 has strong electronic transitions in the visible wavelength region. Upon binding of a substrate molecule (e.g., camphor), the absorption band of cytochrome P450 shifts to shorter wavelength. The event of camphor bindi...

We present a microscopic theory of quantum-size effects in surface-enhanced Raman scattering (SERS) from molecules adsorbed on small metal nanoparticles. In noble-metal nanoparticles, the confining potential has different effect on s-band and d-band electrons. Namely, the spillout of delocalized sp-electrons beyond the classical nanoparticle boundary results in an incomplete embedding of s-elec...

Plasmonic metal nanoparticles supporting localized surface plasmon resonances have attracted a great deal of interest in boosting the light absorption in solar cells. Among the various plasmonic materials, the aluminium nanoparticles recently have become a rising star due to their unique ultraviolet plasmonic resonances, low cost, earth-abundance and high compatibility with the complementary me...

We report an experimental study on magneto-optical (MO) Kerr effects of yttrium-iron garnet (YIG) thin films incorporating Au nanoparticles. The polar MO Kerr spectra in the wavelength between 400 and 800 nm show that, by incorporating the Au nanoparticles, Kerr rotation angles become negative values in the region, where the localized surface plasmon polariton (SPP) resonance of the Au nanopart...

Papaya mosaic virus has been shown to be an efficient adjuvant and vaccine platform in the design and improvement of innovative flu vaccines. So far, all fusions based on the PapMV platform have been located at the C-terminus of the PapMV coat protein. Considering that some epitopes might interfere with the self-assembly of PapMV CP when fused at the C-terminus, we evaluated other possible site...

A peptide sequence N(3)-GVGV-OMe (G: glycine; V: valine) was attached to a benzene 1,3,5-tricarboxamide (BTA) derivative via"click chemistry" to afford a C(3)-symmetric artificial oligopeptide. The key feature of this oligopeptide is that the binding sites (triazole groups formed by click reaction) are located at the center, while the three oligopeptide arms with a strong tendency to assemble a...

Ionic liquids are a stabilizing medium for the in situ synthesis of ruthenium nanoparticles. Herein we show that the addition of molecular polar solutes to the ionic liquid, even in low concentrations, eliminates the role of the ionic liquid 3D structure in controlling the size of ruthenium nanoparticles, and can induce their aggregation. We have performed the synthesis of ruthenium nanoparticl...

A simple strategy to tailor the surface of nanoparticles for their specific adsorption to and localization at block copolymer interfaces was explored. Gold nanoparticles coated by a mixture of low molecular weight thiol end-functional polystyrene (PS-SH) (Mn = 1.5 and 3.4 kg/mol) and poly(2-vinylpyridine) homopolymers (P2VP-SH) (Mn = 1.5 and 3.0 kg/mol) were incorporated into a lamellar poly(st...

a box-behnken design with three replicates was used for preparation and evaluation of eudragit vancomycin (vcm) nanoparticles prepared by double emulsion. the purpose of this work was to optimize vcm nanoparticles to improve the physicochemical properties. nanoparticles were formed by using w1/o/w2 double-emulsion solvent evaporation method using eudragit rs as a retardant material. full factor...

metallic nanoparticles can exhibit very large optical extinction in the visible spectrum due to localized surface plasmon resonance. spherical plasmonic nanoparticles have been the subject of numerous studies in recent years due to the fact that the scattering response of spheres can be analytically evaluated using mie theory. however a major disadvantage of metallic spherical nanoparticles is ...