International Journal of Pharmaceutical Sciences Review and Research Available online at www.globalresearchonline.net 166 Jishan Ali Ahmed*, Arindam Chatterjee, Bhupendra Singh Chauhan, Manish Jaimini, Himanshu M. Varshney M. Pharma ІV sem Pharmaceutics in Jaipur College of Pharmacy, ISI-15, RIICO, Sitapura Institutional Area, Jaipur, Rajasthan, India. Lecturer in Jaipur College of Pharmacy, De...

INTRODUCTION Considerable advances have been made to hydrogels with the development of faster swelling superporous hydrogels (SPHs). These new-generation hydrogels have large numbers of interconnected pores, giving them the capacity to absorb large amounts of water at an accelerated rate. This gives SPHs the ability to be used in a variety of novel drug delivery applications, such as gastric re...

Stimuli-sensitive hydrogels (or smart hydrogels) are hydrogels that swell or shrink in response to small changes in environmental conditions in which they are placed. While the extent of swelling or shrinking may be large, the kinetics of such changes is slow, since the diffusion of water into and out of the hydrogel is a slow process. To obtain fast responses, we have prepared superporous hydr...

The aim of the current research work was to prepare and evaluate different generations of superporous hydrogels (SPH) of acrylamide and chitosan using gas blowing technique and evaluate them for swelling, mechanical properties, FTIR, SEM, XRD, and in vitro drug release. The ingredients used were acrylamide, N,N'-methylene bisacrylamide, chitosan, Pluronic F127, ammonium per sulfate-N,N,N',N'-te...

We recently showed that superporous hydrogel (SPH) scaffolds promote long-term stem cell viability and cell driven mineralization when cells were seeded within the pores of pre-fabricated SPH scaffolds. The possibility of cell encapsulation within the SPH matrix during its fabrication was further explored in this study. The impact of each chemical component used in SPH fabrication and each step...

The preparation of superporous hydrogels based beads (SPHBs) with various concentrations of polymers such as guar gum,sodium alginate and hydroxy propyl cellulose combination. The superporous hydrogels beads containing carbonate salt, as a gas-forming agent, were prepared by dispersing carbonate salt in polymers solution and then extruding into either neutral or acidified solution of calcium ch...

In order to modify the xanthan gum (XG) polysaccharide and to develop the hydrogels meant for the drug delivery, we have prepared XG-g-poly [HEMA-co-AA] superporous hydrogel (SPH) through chemical cross-linking by graft copolymerization of 2-hydroxyethyl methacrylate (HEMA) and acrylic acid (AA) on to XG via redox initiator system of ammonium persulfate (APS) and N, N, N’, N’tetramethylethylene...

During the past few decades, numerous oral drug delivery systems have been developed to act as drug reservoirs from which the active substance can be released over a specific period of time at a predetermined and controlled rate. It is evident from the recent scientific and patent literatures that an increased interest in novel oral controlled release dosage forms that designed to be retained i...