The current trend in liquid chromatography is towards the achievement of higher kinetic efficiency and shorter analysis time. Different types of column packings are now available for attaining very fast and high resolution separations without changing instruments, worrying about high backpressure or compromising column longevity. In recent developments of particle technology, the use of superfi...

In this work, a detailed study of mass transfer properties trans-stilbene oxide (TSO) enantiomers on two Whelk-O1 chiral stationary phases (CSPs) has been performed. The CSPs were prepared by using both fully-porous silica particles 2.5 μm particle diameter and superficially-porous ones 2.6 as base materials. By combining stop-flow dynamic measurements in normal-phase conditions, the different ...