Fluconazole is an effective bis-triazole oral antifungal agent indicated for the treatment of systemic and superficial candidiasis. The clinical pharmacokinetics relative bioavailability (bioequivalence) a single dose new generic formula (capsule) containing 150 mg fluconazole as test product was compared against brand Diflcan® capsule, Pfizer, reference product. Both products were administered...

The recently described species Candida dubliniensis has been recovered primarily from superficial oral candidiasis in HIV-infected patients. No clinically documented invasive infections were reported until now in this patient group or in other immunocompromised patients. We report three cases of candidemia due to this newly emerging Candida species in HIV-negative patients with chemotherapy-ind...

Fungi are a kind of eukaryotic cell organisms widely distributed in nature and considered as independent branches existing organisms. There 1 million to 1.5 fungi the world, most which beneficial humans only few harmful humans. Mycosis is an infectious disease caused by that infect animals. The fungus infects mainly from external environment. route infection can be contact, inhalation or ingest...

Superficial fungal infections of the hair, skin and nails are a major cause of morbidity in the world. Choosing the right treatment is not always simple because of the possibility of drug interactions and side effects. The first part of the article discusses the main treatments for superficial mycoses - keratophytoses, dermatophytosis, candidiasis, with a practical approach to the most commonly...

Candida species represent a major fungal threat for human health. Within the genus, yeast albicans is most frequently incriminated during episodes of candidiasis or candidemia. Biofilm formation used by C. to produce microbial community that important in an infectious context. The cell wall, superficial cellular compartment, paramount importance regarding establishment biofilms. wall contains p...

Superficial fungal infections of the hair, skin and nails are a major cause of morbidity in the world. Choosing the right treatment is not always simple because of the possibility of drug interactions and side effects. The first part of the article discusses the main treatments for superficial mycoses - keratophytoses, dermatophytosis, candidiasis, with a practical approach to the most commonly...

Candidiasis is a common opportunistic oral Candida infection that develops in the presence of one of several predisposing conditions [1,2]. The term Candida originates from the Latin word candid, meaning white. The spores of Candida are a commensal, harmless form of a dimorphic fungus that becomes invasive and pathogenic pseudohyphae when there is a disturbance in the balance of flora or in deb...

Background and Purpose: Candida species are the most common organisms involved in superficial fungal infections, worldwide. Although econazole is among the most frequently used topical formulations for the treatment of candidiasis, no information is available regarding the susceptibility profiles of Candida species in Iran. Materials and Methods: In vitro susceptibility of 100 clinical Candida...

Infants treated in neonatal intensive care units suffer an increased risk for invasive candidiasis, but the diagnosis is sometimes difficult. D-arabinitol is a metabolite of most pathogenic Candida species. An elevated urine D-arabinitol/L-arabinitol (DA/LA) ratio is a sensitive sign of invasive candidiasis in children with cancer, but the method has not been previously evaluated for newborn in...