Andrographis paniculata has been used as a traditional medicine and a predominant constituent in 26 Ayurvedic formulations over the last two decades. Its impact on the male fertility is a controversial from the past few years. In the present study we have investigated the antioxidant enzyme status and the indices of lipid peroxidation in the testis and epididymis of male wistar rats. Male wista...

Hydroalcoholic extract of Andrographis paniculata prevented isoproterenol induced increase in lipid peroxidation and increased the activities of antioxidant enzymes viz. super oxide dismutase, catalase, glutathione peroxidase and the levels of reduced glutathione in hearts. In addition, the extract also prevented the leakage of lactate dehydrogenase from heart and salvages the heart from isopro...

Wistar rats were given a diet with 8% sodium chloride to induce hypertension and subsequently sacrificed. Glycine max powder was used reduce atenolol’s side effects during the trial. Thirty divided into five groups tested over eight weeks. Rats’ blood pressure (BP) measured tail-cuff NIBP monitor. Biochemical markers like TG, TC, HDL, LDL, VLDL, alanine transferase, aspartate lipid peroxide (LP...

Atherosclerosis being considered as an inflammatory disorder, the present study was undertaken to investigate the effectiveness of anti-inflammatory drugs (ibuprofen, aspirin, and celecoxib) in hypercholesterolemia. Ibuprofen is a cyclooxygenase (COX-1 and COX-2) inhibitor known to reduce the production of prostaglandins that play prominent role in inflammation. Beside the anti-inflammatory eff...

The best scientist is open to experience and begins with romance-the idea that anything is possible. Caspase-12 cleavage and increased oxidative stress during motoneuron degeneration in transgenic mouse model of ALS. XIAP decreases caspase-12 cleavage and calpain activity in spinal cord of ALS transgenic mice.tribution and levels of cathepsinD and cystatins in amyotro-phic lateral sclerosis tra...