Sulfur assimilation may limit the pool of methionine and cysteine available for incorporation into zeins, the major seed storage proteins in maize. This hypothesis was tested by producing transgenic maize with deregulated sulfate reduction capacity achieved through leaf-specific expression of the Escherichia coli enzyme 3'-phosphoadenosine-5'-phosphosulfate reductase (EcPAPR) that resulted in h...

BACKGROUND/AIMS We previously reported that acute betaine treatment induced significant changes in the hepatic glutathione and cysteine levels in mice and rats. The present study was aimed to determine the effects of dietary betaine on the metabolism of sulfur-containing amino acids. METHODS/RESULTS Male mice were supplemented with betaine (1%) in drinking water for up to 3 weeks. Changes in ...

methylsulfonylmethane (msm) is a sulfur-containing compound commonly found in diet and known to reduce oxidative stress. this trial was conducted to determine whether single dose supplementation with msm attenuates post-exercise oxidative stress in healthy untrained young men. sixteen untrained men volunteered for this study. participants were randomized in a double-blind placebo-controlled fas...

Methylsulfonylmethane (MSM) is a sulfur-containing compound commonly found in diet and known to reduce oxidative stress. This trial was conducted to determine whether single dose supplementation with MSM attenuates post-exercise oxidative stress in healthy untrained young men. Sixteen untrained men volunteered for this study. Participants were randomized in a double-blind placebo-controlled fas...

Methylsulfonylmethane (MSM) is a sulfur-containing compound commonly found in diet and known to reduce oxidative stress. This trial was conducted to determine whether single dose supplementation with MSM attenuates post-exercise oxidative stress in healthy untrained young men. Sixteen untrained men volunteered for this study. Participants were randomized in a double-blind placebo-controlled fas...

Most studies concerning the influence of dietary protein on serum or plasma lipids have been conducted with experimental animals. A hypocholesterolemic effect has been demonstrated for high dietary protein levels in growing swine, rats, and chicks (1-6). In the rat a hypercholesterolemic diet, containing cholesterol, or cholic acid, or both, is required to demonstrate a substantial depressant e...

The neurodegenerative disorder Friedreich's ataxia (FRDA) is caused by mutations in frataxin, a mitochondrial protein whose function remains controversial. Using co-immunoprecipitation and mass spectrometry we identified multiple interactors of mitochondrial frataxin in mammalian cells. One interactor was mortalin/GRP75, a homolog of the yeast ssq1 chaperone that integrates iron-sulfur clusters...

Abstract Sulfur dioxide is the most used additive today for preventing browning in grape musts and wines. However, since wine consumers are increasingly interested healthier wines, industry keen to reduce its use. Some promising alternatives sulfur have been proposed recent years, including glutathione, both pure form of inactivated yeasts, Metschnikowia pulcherrima as a bioprotective agent. in...

Albomycin (ABM), also known as grisein, is a sulfur-containing metabolite produced by Streptomyces griseus ATCC 700974. Genes predicted to be involved in the biosynthesis of ABM and ABM-like molecules are found in the genomes of other actinomycetes. ABM has potent antibacterial activity, and as a result, many attempts have been made to develop ABM into a drug since the last century. Although th...