The main objective of this study was to examine the feasibility of coupling an electrochemical process with a biological treatment for the degradation of sulfamethazine, a biorecalcitrant antibiotic. The electrochemical behavior of sulfamethazine was examined by cyclic voltammetry, showing an electroactivity in oxidation. The pre-treatment was carried out using an electrochemical flow cell invo...

The interaction of sulfonamide antimicrobial agents with smectite clay minerals and humic acid (HA)-clay complexes was investigated in batch experiments to assess the influence of adsorbed humic acid on sulfonamide sorption. Soil HA-clay complexes were produced at HA:clay ratios of 1:5, 1:50, and 1:100 (w/w). Vibrational and electronic spectroscopy indicated the preferential adsorption of polar...

Background. The control of emergence and spread of infectious diseases depends critically on the details of the genetic makeup of pathogens and hosts, their immunological, behavioral and ecological traits, and the pattern of temporal and spatial contacts among the age/stage-classes of susceptible and infectious host individuals. Methods and Findings. We show that failing to acknowledge the exis...

Aquaculture wastewaters have been used in rice irrigation directly or indirectly. Antibiotics aquaculture wastewater entering the fields with will affect soil physicochemical properties, microbial and nitrogen conversion. A pot experiment irrigated simulated was performed to study effects of sulfamethazine on concentration conversion-related microorganisms different modes. Sulfamethazine (500 n...

SimunekJ., A. B. Siddique, E. Hegerova: Placental Transfer of Suljamethazine in Mice and Rats. Acta Vet. Brno, 47,1978: 145-151. Placental transfer of sulfamethazine in mice was investigated in the second half of their pregnancy. The transfer was not free but only a part of the drug administered to mothers was found to pass from the maternal circulation to the fetus. Placental transfer of sulfa...

A liquid chromatographic (LC) method for determining 14 sulfonamide (SA) (sulfanilamide, sulfadiazine (SDZ), sulfathiazole, sulfapyridine, sulfamerazine (SMR), sulfamethazine (SMZ), sulfamethizole, sulfamethoxypyridazine, sulfachloropyridazine (SCP), sulfamonomethoxine, sulfadoxine, sulfamethoxazole, sulfadimethoxine (SDM), and sulfaquinoxaline (SQX)) residues in edible catfish, shrimp and salm...

New sulfonamides are usually tested against bacteria or diseases wherein the older drugs work satisfactorily. There seems to be little advantage in testing new drugs only against those bacteria in which older sulfonamides have already proved their worth. Since the older sulfonamides exert little action on diseases caused by some gram-negative organisms, it seemed advisable to attempt to find on...

Pharmaceutical compounds represent a rapidly emerging class of environmental contaminants. Such compounds were recently classified by the U.S. Geological Survey, including several antibiotics. An LC-MS/MS screening method for the top five antibiotics in drinking water was developed and validated using a Shimadzu LC-MS-IT-TOF. The separation was performed using a Waters Acquity UPLC BEH C18 colu...

Studies in our laboratories (D. Coffin, D. Gardner, and R. Holzman, Arch. Environ. Health, 16:633, 1968) have shown that air pollutants depress the phagocytic ability of the pulmonary alveolar macrophages (PAM) in rabbits. During the course of these studies, sulfamethazine was administered to some of these animals. It was noted that PAM of sulfamethazine-treated rabbits ingested fewer bacteria ...

Composting of manure may lead to the degradation of veterinary antimicrobials, but it is largely unknown if the presence of antimicrobials affects the composting process. Open-air windrow composting of manure from beef cattle (Bos taurus) administered chlortetracycline, sulfamethazine, and tylosin was investigated in a 2-yr study. At windrow construction, chlortetracycline had extensively isome...