Correlation structure contains important information about longitudinal data. Existing sufficient dimension reduction approaches assuming independence may lead to substantial loss of efficiency. We apply the quadratic inference function to incorporate the correlation information and apply the transformation method to recover the central subspace. The proposed estimators are shown to be consiste...

Awareness of a problem is the first step toward finding solutions. The nephrology community is increasingly aware of the extraordinary morbid and mortal risks within the first year of renal replacement therapy (RRT), especially with in-center dialysis. However, this awareness has not yet been substantially translated to universal or even regional changes in care of patients—changes designed to ...

orally active aromatase inhibitors (ais) have gained attention for treatment of infertile women with endometriosis in whom aromatase p450 is aberrantly expressed. this review aimed to critically appraise and summarize the available evidence concerning the use of ais for management of endometriosis-associated infertility. pubmed was searched to may 2015 with the following key words: endometriosi...

Overseas investigations have shown that many healthcare institutions are understocked of antidotes to treat these patients. 1–4 Despite a recent study to the contrary, 5 the paper by Fountain and colleagues, published in this issue of the New Zealand Medical Journal, suggests similar problems in New Zealand hospitals with shortcomings in hospital pharmacy stocks and resupply. 6 The paper raises...

As public health practitioners from the National Asthma Control Program (NACP) of the Centers for Disease Control and Prevention, we read the essay “From Evidence-Based Medicine to Evidence-Based Health: the Example of Asthma” (1) with great interest. We agree with the authors’ hypothesis that evidence-based clinical medicine must be supplemented by asthma self-management support “that extends ...