The constant evolution of synchrotron structural biology beamlines, the viability of screening protein crystals for a wide range of heavy-atom derivatives, the advent of efficient protein labelling and the availability of automatic data-processing and structure-solution pipelines have combined to make de novo structure solution in macromolecular crystallography a less arduous task. Nevertheless...

This study investigates the relationship between market orientation, intellectual capital, and new product success, and integrates the internal and external views to examine the effects of market orientation and intellectual capital on new product success. Travel agencies within the Taiwan tourism industry were targeted. A questionnaire was mailed to 1000 agencies, yielding 182 valid survey ins...

Experimental conditions or the presence of interacting components can lead to variations in the structural models of macromolecules. However, the role of these factors in conformational selection is often omitted by in silico methods to extract dynamic information from protein structural models. Structures of small peptides, considered building blocks for larger macromolecular structural models...

The aim of this paper is twofold. First, to extend Hodges’ model of relationships between financial planning for retirement with psychosocial variables to predict both objective and subjective measures of financial planning. Second, to apply that model to a representative sample of immigrants in Europe provided by the first wave of SHARE study. Data from 1272 immigrants in Europe were obtained ...

We introduce a method for finding a characteristic substructure for a set of molecular structures. Different from common approaches, such as computing the maximum common subgraph, the resulting substructure does not have to be contained in its exact form in all input molecules. Our approach is part of the identification pipeline for unknown metabolites using fragmentation trees. Searching datab...

Structural biology elucidates atomic structures of macromolecules such as proteins, DNA, RNA, and their complexes to understand the basic mechanisms of their functions. Among proteins that pose the most difficult problems to current efforts are those which have several large domains connected by long, flexible polypeptide segments. Although abundant and critically important in biological cells,...

Structural equation modeling (SEM) provides a dependable framework for testing differences among groups on latent variables (constructs, factors). The purpose of this article is to illustrate SEM-based testing for group mean differences on latent variables. Related procedures of confirmatory factor analysis and testing for measurement invariance across compared groups are also presented in the ...

A theoretical framework model that researches the interrelationship of organizational innovation, organizational performance and dynamic core competence of enterprise (DCCE) is proposed on the foundation of the analysis of measure dimensions which include four oriented organizational innovations and the four sub-core capabilities of DCCE and the three levels of variables of performance. By usin...

The concept of livable city was put forward naturally and began to gain more attention when people care more about human needs during the economic development. In this paper, we define a livable city as an urban area takes the residents’ demand as first priority. It has a pleasant ecological environment, a mature community with rich public resources such as culture, transportation and medical s...

Computational modelling of proteins has been a major catalyst in structural biology. Bioinformatics groups have exploited the repositories of known structures to predict high-quality structural models with high efficiency at low cost. This article provides an overview of comparative modelling, reviews recent developments and describes resources dedicated to large-scale comparative modelling of ...