Background. Migraine is prevalent in young patients and a frequent stroke mimic. To distinguish stroke mimics from true stroke can be difficult, and there is a possibility of misdiagnosing a stroke as a migrainous attack in patients with migraine. We aimed to investigate if a history of migraine affects the rate of thrombolytic therapy in young stroke patients. Methods. All patients below 50 ye...

Migraine is a common, disabling, and undertreated episodic brain disorder that is more common in women than in men. Unbiased genome-wide association studies have identified 13 migraine-associated variants pointing at genes that cluster in pathways for glutamatergic neurotransmission, synaptic function, pain sensing, metalloproteinases, and the vasculature. The individual pathogenetic contributi...

Objective To investigate the association between migraine and ischaemic or haemorrhagic stroke in young women. Design Hospital based case-control study. Setting Five European centres participating in the World Health Organisation Collaborative Study of Cardiovascular Disease and Steroid Hormone Contraception. Subjects 291 women aged 20-44 years with ischaemic, haemorrhagic, or unclassified arte...

BACKGROUND AND PURPOSE Migraine with aura (MA) is considered as a risk factor for ischaemic stroke. The present observational retrospective study compares migraine patients admitted for a documented stroke with those presenting focal neurological symptoms and headache without a demonstrable lesion and in which the final diagnosis was a migraine attack with aura. MATERIAL AND METHODS The study...

OBJECTIVE To investigate the association between migraine and ischaemic or haemorrhagic stroke in young women. DESIGN Hospital based case-control study. SETTING Five European centres participating in the World Health Organisation Collaborative Study of Cardiovascular Disease and Steroid Hormone Contraception. SUBJECTS 291 women aged 20-44 years with ischaemic, haemorrhagic, or unclassifie...

BACKGROUND Studies have linked migraine with aura to an increased risk of ischemic stroke, particularly among women. Data on the relationship of migraine and functional outcome from ischemic cerebral events are sparse. METHODS AND RESULTS This was a prospective cohort study among 27 852 women enrolled in the Women's Health Study for whom we had information on migraine and measured cholesterol...

OBJECTIVE  To evaluate whether patients with migraine are at increased risk of perioperative ischemic stroke and whether this may lead to an increased hospital readmission rate. DESIGN  Prospective hospital registry study. SETTING  Massachusetts General Hospital and two satellite campuses between January 2007 and August 2014. PARTICIPANTS  124 558 surgical patients (mean age 52.6 years; 5...

introduction: spreading depression (sd) is a propagating wave of depolarization followed by depression of the neuroglial activities and can modulate extracellular dopamine concentrations in the neocortex. it has been shown that the dopaminergic system plays a role in migraine. sd has been suggested as a critical phenomenon in the pathophysiology of migraine. the aim of this study was to investi...

Background—Studies have linked migraine with aura to an increased risk of ischemic stroke, particularly among women. Data on the relationship of migraine and functional outcome from ischemic cerebral events are sparse. Methods and Results—This was a prospective cohort study among 27 852 women enrolled in the Women’s Health Study for whom we had information on migraine and measured cholesterol v...