نتایج جستجو برای: streptozotoci induced diabetes
تعداد نتایج: 1246171 فیلتر نتایج به سال:
Background and Objective: liver disease is highly prevalent in type 2 diabetes mellitus (T2DM) and exercise training is effective in preventing and treating diabetes-induced hepatic injury. Therefore, the aim of this study was to assess the effect of chronic swimming exercise on the hepatic matrix metalloproteinase 2 (MMP-2) activity and tumor necrosis factor-α (TNF-α) level of live...
abstract background and objective: diabetes mellitus is associated with cardiomyopathic changes, can be mediated by an oxidative stress. we aimed to study the effects of regular aerobic training and arbutin supplementation on total oxidant status (tos) and total antioxidant (tas) status in the cardiac tissue of diabetic rats. material and methods: fourty-two male wistar rats with an average wei...
Background and Objective: The tissue oxidative stress is the most important factor in the development of diabetic kidney disease. The purpose of this study was to evaluate the therapeutic effect of swimming training and Arbutin supplement on diabetes-induced renal oxidative stress. Materials and Methods: 42 male Wistar rats were randomly divided into 6 groups (7 rats per group) of control, d...
background: the most devastating manifestations of diabetes mellitus are vascular complications. although there are many factors involved in the pathogenesis of diabetic vasculopathy, many studies suggest a role for glucose–induced oxidative stress. studies in animal models, have demonstrated that the administration of antioxidants restores normal endothelial functions. the study was designed t...
objective(s): reproductive dysfunction is a consequence of diabetes. diabetes is associated with changes in testicular tissue. sesame oil contains large amounts of polyunsaturated fatty acids and lignin with antioxidant activity, vitamin e, and monounsaturated fatty acid (mufa). the present study investigated the effects of sesame on testis histology and male reproductive parameters in streptoz...
The BioBreeding- Diabetes Prone (BB-DP) rat spontaneously develops an autoimmune diabetic syndrome that is dependent on the RT1 u Major Histocompatibility Complex (MHC) haplotype and homozygosity for an allele at the Lymphopenia (Lyp) locus. Lyp mutation is responsible for a peripheral T -lymphopenia. There are other genetic loci contributing to diabetes susceptibility in this strain. BB ra...
Background and Aim: Pemphigus vulgaris is the most common autoimmune blistering disease. Prednisone, commonly in combination with an immunosuppressive adjuvant such as azathioprine or cyclophosphamide, is the standard treatment for pemphigus vulgaris. Approximately 5% to 15% of mortality of the disease is due to the complications of corticosteroids therapy. The aim of this study was to determin...
background: the global prevalence of diabetes mellitus is on rise. diabetes-induced oxidative stress has been known to affect liver, pancreas, kidney and reproductive organs pathologically. honey is a natural product of bee with antioxidant properties. objective: current study aimed to analyze the protective effects of metformin (mf) alone and mf+ natural honey co-administration on diabetes-ind...
Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorders in reproductive age women. These women confer with complications of pregnancy such as gestational diabetes, pregnancy-induced hypertension, preeclampsia and neonatal complications such as small for gestational diabetes (SGA) are more prevalence in women with PCOS. The aim of this study was to evaluate the incide...
Context: Gestational diabetes is defined as carbohydrate intolerance with onset or first recognition during pregnancy. Diabetes during pregnancy increases the incidences of congenital anomalies, in a mother and her embryo. Oxidative stress has been implicated to be responsible in diabetic embryopathy. Objective: In this study, we used nanoceria as an antioxidant for amelioration of diabetic embry...
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