Sydenham’s chorea is a delayed complication of group Aßhaemolytic streptococcal infections and forms one of the majorcriteria of acute rheumatic fever.It is characterised bychorea, muscular weakness, and a number of neuropsychiatricsymptoms. It is considered to be an autoantibody mediated disorderwith the evidence suggesting that patients with Sydenham’schorea produce antibodies that cross reac...

conclusions although lap had good performance in early diagnosis of gas, a combination of clinical findings, including tonsillar exudates, petechiae with results of rapid antigen test or culture is necessary for clinician judgment. throat culture is the gold standard test for detecting group a streptococcal infection, but rapid test is a good replacement for culture. objectives the aim of this ...

The annual incidence of invasive group A streptococcal disease in the developed world has been stable for at least 2 decades at 2.0–4.0 cases per 100,000 persons per year [1–3]. Streptococcal toxic shock syndrome (TSS) and necrotizing fasciitis are among the most severe manifestations of invasive group A streptococcal infection, with case-fatality rates of 30%-70% in adult patients with strepto...

G ROUP A streptococcal infection initiates acute rheumatic fever; rheumatic valvular heart disease is a sequela that develops during or subsequent to the acute rheumatic episode. The mechanism by which the preceding streptococcal infection produces the arthritic and constitutional symptoms and valvular heart disease is unknown. Regardless of the mechanism involved, there is little doubt that pr...

G ROUP A streptococcal infection initiates acute rheumatic fever; rheumatic valvular heart disease is a sequela that develops during or subsequent to the acute rheumatic episode. The mechanism by which the preceding streptococcal infection produces the arthritic and constitutional symptoms and valvular heart disease is unknown. Regardless of the mechanism involved, there is little doubt that pr...

The association between acute renal disease and infection has been known since the mid ‘800s. PIGN is a reactive immunological process against kidney secondary to an infection, classically caused by Streptococcus. Because usually ongoing at time GN diagnosed, term infection-related glomerulonephritis (IRGN) proposed. Acute post-streptococcal [APSGN] most common form of encountered in children. ...

In the past decade there has been renewed interest in psychiatric and movement dis-interest in psychiatric and movement disorders that develop in the context of orders that develop in the context of streptococcal infection. There is increasing streptococcal infection. There is increasing evidence that these disorders are auto-evidence that these disorders are auto-immune and are mediated by ant...

The observation that individuals who acquire rheumatic fever following a streptococcal infection usually respond with higher streptococcal antibody titres than those who have streptococcal infections uncomplicated by rheumatic fever has been reported repeatedly (1-7). There are exceptions, but, if rheumatics are considered as a group, this observation seems to hold true and it has led to an ass...